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Abstract
Multi-resonant thermally activated delayed fluorescence (MR-TADF) emitters have attracted strong interest for organic electroluminescent devices due to their high photoluminescence quantum yield (ΦPL) and narrowband emission. These properties are also crucial for high-performance biological probes, especially red emitters. Orange and red MR-TADF emitters, PhDPA-DiKTa and MeODPA-DiKTa, are designed by decorating the DiKTa core with di([1,1′-biphenyl]-4-yl)amine and bis(4-methoxyphenyl)amine, respectively. As 5 wt.% doped films in 1,3-di(9H-carbazol-9-yl)benzene (mCP), PhDPA-DiKTa emits at λPL of 617 nm, while MeODPA-DiKTa emits at λPL of 655 nm. Both show delayed fluorescence, with delayed lifetimes, τd, of 658.4 and 249.2 µs, respectively. Water-dispersible glassy organic dots (g-Odots) based on these materials are prepared by encapsulating them and mCP host into an amphiphilic DSPE-PEG2k polymer. Both families of g-Odots showed a deeper red emission and enhanced ΦPL compared to the corresponding 5 wt.% doped films in mCP (λPL = 618 nm, ΦPL = 77% for PhDPA-DiKTa g-Odots, λPL = 663 nm, ΦPL = 38% for MeODPA-DiKTa g-Odots). The TADF character of the emitters is conserved in the g-ODots, with τd of 203.9 µs for PhDPA-DiKTa g-Odots and 131.6 µs for MeODPA-DiKTa g-Odots. These MR-TADF g-Odots are successfully demonstrated as biological imaging probes of HeLa cells.
Original language | English |
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Number of pages | 9 |
Journal | Advanced Optical Materials |
Volume | Early View |
Early online date | 29 Nov 2024 |
DOIs | |
Publication status | E-pub ahead of print - 29 Nov 2024 |
Keywords
- Glassy organic dots
- Multi-resonance
- Nanoparticles bioimaging
- Red emitters
- Thermally activated delayed fluorescence (TADF)
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Allan Watson Programme Grant: Boron: Beyond the Reagent
Watson, A. J. B. (PI), Morris, R. E. (CoI), Smith, A. D. (CoI) & Zysman-Colman, E. (CoI)
1/05/23 → 30/04/28
Project: Standard
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Chemistry EPSRC-JSPS: EPSRC-JSPS Core-to-Core Grant Application
Zysman-Colman, E. (PI)
1/08/18 → 31/01/24
Project: Standard
Datasets
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Red Multi-Resonant Thermally Activated Delayed Fluorescence Emitters as Bioimaging Agents (dataset)
Si, C. (Creator), Primrose, W. L. (Creator), Xu, Y. (Creator), Hudson, Z. M. (Creator) & Zysman-Colman, E. (Creator), University of St Andrews, 12 Dec 2024
DOI: 10.17630/c11a83a0-b368-4b07-8440-6e79d47058cb
Dataset
File