REASSURED diagnostics to inform disease control strategies, strengthen health systems and improve patient outcomes

Kevin J Land; Debrah I Boeras; Xiang-Sheng Chen; Andrew R Ramsay; Rosanna W Peeling

doi:10.1038/s41564-018-0295-3

REASSURED diagnostics to inform disease control strategies, strengthen health systems and improve patient outcomes

Kevin J Land, Debrah I Boeras, Xiang-Sheng Chen, Andrew R Ramsay, Rosanna W Peeling

Research output: Contribution to journal › Review article › peer-review

Abstract

Lack of access to quality diagnostics remains a major contributor to health burden in resource-limited settings. It has been more than 10 years since ASSURED (affordable, sensitive, specific, user-friendly, rapid, equipment-free, delivered) was coined to describe the ideal test to meet the needs of the developing world. Since its initial publication, technological innovations have led to the development of diagnostics that address the ASSURED criteria, but challenges remain. From this perspective, we assess factors contributing to the success and failure of ASSURED diagnostics, lessons learnt in the implementation of ASSURED tests over the past decade, and highlight additional conditions that should be considered in addressing point-of-care needs. With rapid advances in digital technology and mobile health (m-health), future diagnostics should incorporate these elements to give us REASSURED diagnostic systems that can inform disease control strategies in real-time, strengthen the efficiency of health care systems and improve patient outcomes.

Original language	English
Pages (from-to)	46-54
Number of pages	9
Journal	Nature Microbiology
Volume	4
Issue number	1
DOIs	https://doi.org/10.1038/s41564-018-0295-3
Publication status	Published - Jan 2019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Communicable Disease Control/methods
Communicable Diseases/diagnosis
Diagnostic Services
HIV Infections/diagnosis
Humans
Malaria/diagnosis
Point-of-Care Systems
Syphilis/diagnosis
Tuberculosis, Pulmonary/diagnosis

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10.1038/s41564-018-0295-3

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title = "REASSURED diagnostics to inform disease control strategies, strengthen health systems and improve patient outcomes",

abstract = "Lack of access to quality diagnostics remains a major contributor to health burden in resource-limited settings. It has been more than 10 years since ASSURED (affordable, sensitive, specific, user-friendly, rapid, equipment-free, delivered) was coined to describe the ideal test to meet the needs of the developing world. Since its initial publication, technological innovations have led to the development of diagnostics that address the ASSURED criteria, but challenges remain. From this perspective, we assess factors contributing to the success and failure of ASSURED diagnostics, lessons learnt in the implementation of ASSURED tests over the past decade, and highlight additional conditions that should be considered in addressing point-of-care needs. With rapid advances in digital technology and mobile health (m-health), future diagnostics should incorporate these elements to give us REASSURED diagnostic systems that can inform disease control strategies in real-time, strengthen the efficiency of health care systems and improve patient outcomes.",

keywords = "Communicable Disease Control/methods, Communicable Diseases/diagnosis, Diagnostic Services, HIV Infections/diagnosis, Humans, Malaria/diagnosis, Point-of-Care Systems, Syphilis/diagnosis, Tuberculosis, Pulmonary/diagnosis",

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doi = "10.1038/s41564-018-0295-3",

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AU - Land, Kevin J

AU - Boeras, Debrah I

AU - Chen, Xiang-Sheng

AU - Ramsay, Andrew R

AU - Peeling, Rosanna W

PY - 2019/1

Y1 - 2019/1

N2 - Lack of access to quality diagnostics remains a major contributor to health burden in resource-limited settings. It has been more than 10 years since ASSURED (affordable, sensitive, specific, user-friendly, rapid, equipment-free, delivered) was coined to describe the ideal test to meet the needs of the developing world. Since its initial publication, technological innovations have led to the development of diagnostics that address the ASSURED criteria, but challenges remain. From this perspective, we assess factors contributing to the success and failure of ASSURED diagnostics, lessons learnt in the implementation of ASSURED tests over the past decade, and highlight additional conditions that should be considered in addressing point-of-care needs. With rapid advances in digital technology and mobile health (m-health), future diagnostics should incorporate these elements to give us REASSURED diagnostic systems that can inform disease control strategies in real-time, strengthen the efficiency of health care systems and improve patient outcomes.

AB - Lack of access to quality diagnostics remains a major contributor to health burden in resource-limited settings. It has been more than 10 years since ASSURED (affordable, sensitive, specific, user-friendly, rapid, equipment-free, delivered) was coined to describe the ideal test to meet the needs of the developing world. Since its initial publication, technological innovations have led to the development of diagnostics that address the ASSURED criteria, but challenges remain. From this perspective, we assess factors contributing to the success and failure of ASSURED diagnostics, lessons learnt in the implementation of ASSURED tests over the past decade, and highlight additional conditions that should be considered in addressing point-of-care needs. With rapid advances in digital technology and mobile health (m-health), future diagnostics should incorporate these elements to give us REASSURED diagnostic systems that can inform disease control strategies in real-time, strengthen the efficiency of health care systems and improve patient outcomes.

KW - Communicable Disease Control/methods

KW - Communicable Diseases/diagnosis

KW - Diagnostic Services

KW - HIV Infections/diagnosis

KW - Humans

KW - Malaria/diagnosis

KW - Point-of-Care Systems

KW - Syphilis/diagnosis

KW - Tuberculosis, Pulmonary/diagnosis

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DO - 10.1038/s41564-018-0295-3

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SN - 2058-5276

VL - 4

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EP - 54

JO - Nature Microbiology

JF - Nature Microbiology

IS - 1

ER -

REASSURED diagnostics to inform disease control strategies, strengthen health systems and improve patient outcomes

Abstract

UN SDGs

Keywords

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