Rationalising the effect of reducing agent on the oxazaborolidine-mediated asymmetric reduction of N-substituted imines

Eirene HM Kirton; Gary Tughan; Russell Edward Morris; Robert A Field

doi:10.1016/j.tetlet.2003.11.021

Rationalising the effect of reducing agent on the oxazaborolidine-mediated asymmetric reduction of N-substituted imines

Eirene HM Kirton, Gary Tughan, Russell Edward Morris, Robert A Field

Research output: Contribution to journal › Article › peer-review

Abstract

Comparing the effect of borane-based reducing agents on the stereochemical outcome of oxazaborolidine-mediated ketone and N-substituted imine reduction highlights the potential importance of reducing agent structure on the asymmetric sense of imine reduction. (C) 2003 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	853-855
Number of pages	3
Journal	Tetrahedron Letters
Volume	45
Issue number	4
DOIs	https://doi.org/10.1016/j.tetlet.2003.11.021
Publication status	Published - 19 Jan 2004

Keywords

ENANTIOSELECTIVE SYNTHESIS
CHIRAL OXAZABOROLIDINES
BORANE REDUCTION
KETONES
3,3,3-TRIFLUOROALANINE
CATALYSTS

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title = "Rationalising the effect of reducing agent on the oxazaborolidine-mediated asymmetric reduction of N-substituted imines",

abstract = "Comparing the effect of borane-based reducing agents on the stereochemical outcome of oxazaborolidine-mediated ketone and N-substituted imine reduction highlights the potential importance of reducing agent structure on the asymmetric sense of imine reduction. (C) 2003 Elsevier Ltd. All rights reserved.",

keywords = "ENANTIOSELECTIVE SYNTHESIS, CHIRAL OXAZABOROLIDINES, BORANE REDUCTION, KETONES, 3,3,3-TRIFLUOROALANINE, CATALYSTS",

author = "Kirton, \{Eirene HM\} and Gary Tughan and Morris, \{Russell Edward\} and Field, \{Robert A\}",

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T1 - Rationalising the effect of reducing agent on the oxazaborolidine-mediated asymmetric reduction of N-substituted imines

AU - Kirton, Eirene HM

AU - Tughan, Gary

AU - Morris, Russell Edward

AU - Field, Robert A

PY - 2004/1/19

Y1 - 2004/1/19

N2 - Comparing the effect of borane-based reducing agents on the stereochemical outcome of oxazaborolidine-mediated ketone and N-substituted imine reduction highlights the potential importance of reducing agent structure on the asymmetric sense of imine reduction. (C) 2003 Elsevier Ltd. All rights reserved.

AB - Comparing the effect of borane-based reducing agents on the stereochemical outcome of oxazaborolidine-mediated ketone and N-substituted imine reduction highlights the potential importance of reducing agent structure on the asymmetric sense of imine reduction. (C) 2003 Elsevier Ltd. All rights reserved.

KW - ENANTIOSELECTIVE SYNTHESIS

KW - CHIRAL OXAZABOROLIDINES

KW - BORANE REDUCTION

KW - KETONES

KW - 3,3,3-TRIFLUOROALANINE

KW - CATALYSTS

UR - https://www.scopus.com/pages/publications/0346787842

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DO - 10.1016/j.tetlet.2003.11.021

M3 - Article

SN - 0040-4039

VL - 45

SP - 853

EP - 855

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 4

ER -

Rationalising the effect of reducing agent on the oxazaborolidine-mediated asymmetric reduction of N-substituted imines

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Keywords

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