Rationalising the effect of reducing agent on the oxazaborolidine-mediated asymmetric reduction of N-substituted imines

Eirene HM Kirton; Gary Tughan; Russell Edward Morris; Robert A Field

doi:10.1016/j.tetlet.2003.11.021

Rationalising the effect of reducing agent on the oxazaborolidine-mediated asymmetric reduction of N-substituted imines

Eirene HM Kirton, Gary Tughan, Russell Edward Morris, Robert A Field

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

Comparing the effect of borane-based reducing agents on the stereochemical outcome of oxazaborolidine-mediated ketone and N-substituted imine reduction highlights the potential importance of reducing agent structure on the asymmetric sense of imine reduction. (C) 2003 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	853-855
Number of pages	3
Journal	Tetrahedron Letters
Volume	45
Issue number	4
DOIs	https://doi.org/10.1016/j.tetlet.2003.11.021
Publication status	Published - 19 Jan 2004

Keywords

ENANTIOSELECTIVE SYNTHESIS
CHIRAL OXAZABOROLIDINES
BORANE REDUCTION
KETONES
3,3,3-TRIFLUOROALANINE
CATALYSTS

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abstract = "Comparing the effect of borane-based reducing agents on the stereochemical outcome of oxazaborolidine-mediated ketone and N-substituted imine reduction highlights the potential importance of reducing agent structure on the asymmetric sense of imine reduction. (C) 2003 Elsevier Ltd. All rights reserved.",

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AU - Morris, Russell Edward

AU - Field, Robert A

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KW - CHIRAL OXAZABOROLIDINES

KW - BORANE REDUCTION

KW - KETONES

KW - 3,3,3-TRIFLUOROALANINE

KW - CATALYSTS

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JO - Tetrahedron Letters

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ER -

Rationalising the effect of reducing agent on the oxazaborolidine-mediated asymmetric reduction of N-substituted imines

Abstract

Keywords

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