Projects per year
Abstract
As an alternative to conventional asymmetric hydroformylation (AHF), Asymmetric Transfer Hydroformylation (ATHF) using formaldehyde as a surrogate for syngas is reported. A catalyst derived from commercially available [Rh(acac)(CO)2] and Ph-BPE stands out in terms of both activity and enantioselectivity. Remarkably, not only are high selectivities achievable, the reactions are very simple to carry out, and can give higher enantioselectivity (up to 96% e.e.) and/or turnover frequencies than those that are achievable using the same catalyst (or other leading catalysts) using typical conditions for AHF.
Original language | English |
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Pages (from-to) | 10645-10649 |
Journal | Chemistry - A European Journal |
Volume | 21 |
Issue number | 30 |
Early online date | 25 Jun 2015 |
DOIs | |
Publication status | Published - 14 Jul 2015 |
Keywords
- Enantioselective Catalysis
- Microwave
- Carbinylation
- Hydroformylation
- Formaldehyde
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Dive into the research topics of 'Rapid asymmetric transfer hydroformylation (ATHF) of disubstituted alkenes using paraformaldehyde as a syngas surrogate'. Together they form a unique fingerprint.Projects
- 2 Finished
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Enantioselective Carbonylations: New Insights New Catalysts and New Processes using Enantioselective Carbonylations
Clarke, M. (PI) & Buehl, M. (CoI)
1/09/14 → 30/11/17
Project: Standard
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Industry Fellowship 2012: Catalytic Enantioslective Alkene Carbonylation
Clarke, M. (PI)
1/09/12 → 31/08/14
Project: Fellowship