Quantum Dot Superluminescent Diodes for Optical Coherence Tomography: Skin Imaging

Nikola Krstajic, Louise E. Smith, Stephen John Matcher, David T. D. Childs, Marco Bonesi, Purnima Daisy Lydia Greenwood, Maxime Hugues, Kenneth Kennedy, Mark Hopkinson, Kristian Michael Groom, Sheila MacNeil, Richard A. Hogg, Rod Smallwood

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)

Abstract

We present a high-power (18 mW continuous wave exiting a single-mode fiber and 35 mW exiting the facet), broadband (85 nm full-width at half-maximum) quantum dot-based superluminescent diode, and apply it to a time-domain optical coherence tomography (OCT) setup. First, we test its performance with increasing optical feedback. Then we demonstrate its imaging properties on tissue-engineered (TE) skin and in vivo skin. OCT allows the tracking of epidermal development in TE skin, while the higher power source allows better sensitivity and depth penetration for imaging of in vivo skin layers.

Original languageEnglish
Pages (from-to)748-754
Number of pages7
JournalIEEE Journal of Selected Topics in Quantum Electronics
Volume16
Issue number4
DOIs
Publication statusPublished - 2010

Keywords

  • Optical coherence tomography (OCT)
  • skin imaging
  • superluminescent diodes
  • tissue engineering
  • LIGHT-EMITTING-DIODES
  • EPIDERMAL THICKNESS
  • DELAY-LINE
  • HIGH-POWER
  • KERATINOCYTES
  • TISSUE
  • PERFORMANCE
  • DERMATOLOGY
  • SCATTERING
  • SPECTRUM

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