Quantum Dot Superluminescent Diodes for Optical Coherence Tomography: Skin Imaging

Nikola Krstajic; Louise E. Smith; Stephen John Matcher; David T. D. Childs; Marco Bonesi; Purnima Daisy Lydia Greenwood; Maxime Hugues; Kenneth Kennedy; Mark Hopkinson; Kristian Michael Groom; Sheila MacNeil; Richard A. Hogg; Rod Smallwood

doi:10.1109/JSTQE.2009.2038597

Quantum Dot Superluminescent Diodes for Optical Coherence Tomography: Skin Imaging

Nikola Krstajic, Louise E. Smith, Stephen John Matcher, David T. D. Childs, Marco Bonesi, Purnima Daisy Lydia Greenwood, Maxime Hugues, Kenneth Kennedy, Mark Hopkinson, Kristian Michael Groom, Sheila MacNeil, Richard A. Hogg, Rod Smallwood

School of Physics and Astronomy

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Abstract

We present a high-power (18 mW continuous wave exiting a single-mode fiber and 35 mW exiting the facet), broadband (85 nm full-width at half-maximum) quantum dot-based superluminescent diode, and apply it to a time-domain optical coherence tomography (OCT) setup. First, we test its performance with increasing optical feedback. Then we demonstrate its imaging properties on tissue-engineered (TE) skin and in vivo skin. OCT allows the tracking of epidermal development in TE skin, while the higher power source allows better sensitivity and depth penetration for imaging of in vivo skin layers.

Original language	English
Pages (from-to)	748-754
Number of pages	7
Journal	IEEE Journal of Selected Topics in Quantum Electronics
Volume	16
Issue number	4
DOIs	https://doi.org/10.1109/JSTQE.2009.2038597
Publication status	Published - 2010

Keywords

Optical coherence tomography (OCT)
skin imaging
superluminescent diodes
tissue engineering
LIGHT-EMITTING-DIODES
EPIDERMAL THICKNESS
DELAY-LINE
HIGH-POWER
KERATINOCYTES
TISSUE
PERFORMANCE
DERMATOLOGY
SCATTERING
SPECTRUM

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Krstajic, N., Smith, L. E., Matcher, S. J., Childs, D. T. D., Bonesi, M., Greenwood, P. D. L., Hugues, M., Kennedy, K., Hopkinson, M., Groom, K. M., MacNeil, S., Hogg, R. A., & Smallwood, R. (2010). Quantum Dot Superluminescent Diodes for Optical Coherence Tomography: Skin Imaging. IEEE Journal of Selected Topics in Quantum Electronics, 16(4), 748-754. https://doi.org/10.1109/JSTQE.2009.2038597

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title = "Quantum Dot Superluminescent Diodes for Optical Coherence Tomography: Skin Imaging",

abstract = "We present a high-power (18 mW continuous wave exiting a single-mode fiber and 35 mW exiting the facet), broadband (85 nm full-width at half-maximum) quantum dot-based superluminescent diode, and apply it to a time-domain optical coherence tomography (OCT) setup. First, we test its performance with increasing optical feedback. Then we demonstrate its imaging properties on tissue-engineered (TE) skin and in vivo skin. OCT allows the tracking of epidermal development in TE skin, while the higher power source allows better sensitivity and depth penetration for imaging of in vivo skin layers.",

keywords = "Optical coherence tomography (OCT), skin imaging, superluminescent diodes, tissue engineering, LIGHT-EMITTING-DIODES, EPIDERMAL THICKNESS, DELAY-LINE, HIGH-POWER, KERATINOCYTES, TISSUE, PERFORMANCE, DERMATOLOGY, SCATTERING, SPECTRUM",

author = "Nikola Krstajic and Smith, {Louise E.} and Matcher, {Stephen John} and Childs, {David T. D.} and Marco Bonesi and Greenwood, {Purnima Daisy Lydia} and Maxime Hugues and Kenneth Kennedy and Mark Hopkinson and Groom, {Kristian Michael} and Sheila MacNeil and Hogg, {Richard A.} and Rod Smallwood",

year = "2010",

doi = "10.1109/JSTQE.2009.2038597",

language = "English",

volume = "16",

pages = "748--754",

journal = "IEEE Journal of Selected Topics in Quantum Electronics",

issn = "1077-260X",

publisher = "IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC",

number = "4",

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Krstajic, N, Smith, LE, Matcher, SJ, Childs, DTD, Bonesi, M, Greenwood, PDL, Hugues, M, Kennedy, K, Hopkinson, M, Groom, KM, MacNeil, S, Hogg, RA & Smallwood, R 2010, 'Quantum Dot Superluminescent Diodes for Optical Coherence Tomography: Skin Imaging', IEEE Journal of Selected Topics in Quantum Electronics, vol. 16, no. 4, pp. 748-754. https://doi.org/10.1109/JSTQE.2009.2038597

TY - JOUR

T1 - Quantum Dot Superluminescent Diodes for Optical Coherence Tomography: Skin Imaging

AU - Krstajic, Nikola

AU - Smith, Louise E.

AU - Matcher, Stephen John

AU - Childs, David T. D.

AU - Bonesi, Marco

AU - Greenwood, Purnima Daisy Lydia

AU - Hugues, Maxime

AU - Kennedy, Kenneth

AU - Hopkinson, Mark

AU - Groom, Kristian Michael

AU - MacNeil, Sheila

AU - Hogg, Richard A.

AU - Smallwood, Rod

PY - 2010

Y1 - 2010

N2 - We present a high-power (18 mW continuous wave exiting a single-mode fiber and 35 mW exiting the facet), broadband (85 nm full-width at half-maximum) quantum dot-based superluminescent diode, and apply it to a time-domain optical coherence tomography (OCT) setup. First, we test its performance with increasing optical feedback. Then we demonstrate its imaging properties on tissue-engineered (TE) skin and in vivo skin. OCT allows the tracking of epidermal development in TE skin, while the higher power source allows better sensitivity and depth penetration for imaging of in vivo skin layers.

AB - We present a high-power (18 mW continuous wave exiting a single-mode fiber and 35 mW exiting the facet), broadband (85 nm full-width at half-maximum) quantum dot-based superluminescent diode, and apply it to a time-domain optical coherence tomography (OCT) setup. First, we test its performance with increasing optical feedback. Then we demonstrate its imaging properties on tissue-engineered (TE) skin and in vivo skin. OCT allows the tracking of epidermal development in TE skin, while the higher power source allows better sensitivity and depth penetration for imaging of in vivo skin layers.

KW - Optical coherence tomography (OCT)

KW - skin imaging

KW - superluminescent diodes

KW - tissue engineering

KW - LIGHT-EMITTING-DIODES

KW - EPIDERMAL THICKNESS

KW - DELAY-LINE

KW - HIGH-POWER

KW - KERATINOCYTES

KW - TISSUE

KW - PERFORMANCE

KW - DERMATOLOGY

KW - SCATTERING

KW - SPECTRUM

U2 - 10.1109/JSTQE.2009.2038597

DO - 10.1109/JSTQE.2009.2038597

M3 - Article

SN - 1077-260X

VL - 16

SP - 748

EP - 754

JO - IEEE Journal of Selected Topics in Quantum Electronics

JF - IEEE Journal of Selected Topics in Quantum Electronics

IS - 4

ER -

Quantum Dot Superluminescent Diodes for Optical Coherence Tomography: Skin Imaging

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