Phosphine containing oligonucleotides for the development of metallodeoxyribozymes

Loic Ropartz, Nico J. Meeuwenoord, Gijsbert A. van der Marel, Piet W. N. M. van Leeuwen, Alexandra M. Z. Slawin, Paul C. J. Kamer

Research output: Contribution to journalArticlepeer-review

47 Citations (Scopus)

Abstract

Novel transition metal catalysts based on oligonucleotides can be easily obtained by functionalization of 5-iodouridine with phosphine ligands, resulting in good asymmetric induction in palladium catalyzed allylic nucleophilic substitution.

Original languageEnglish
Pages (from-to)1556-1558
Number of pages3
JournalChemical Communications
Issue number15
DOIs
Publication statusPublished - Feb 2007

Keywords

  • ASYMMETRIC HYDROGENATION
  • DNA
  • CATALYSIS
  • ENZYMES
  • CHEMISTRY
  • EVOLUTION
  • RNA

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