Phosphine containing oligonucleotides for the development of metallodeoxyribozymes

Loic Ropartz; Nico J. Meeuwenoord; Gijsbert A. van der Marel; Piet W. N. M. van Leeuwen; Alexandra M. Z. Slawin; Paul C. J. Kamer

doi:10.1039/b617871e

Phosphine containing oligonucleotides for the development of metallodeoxyribozymes

Loic Ropartz, Nico J. Meeuwenoord, Gijsbert A. van der Marel, Piet W. N. M. van Leeuwen, Alexandra M. Z. Slawin, Paul C. J. Kamer

Research output: Contribution to journal › Article › peer-review

Abstract

Novel transition metal catalysts based on oligonucleotides can be easily obtained by functionalization of 5-iodouridine with phosphine ligands, resulting in good asymmetric induction in palladium catalyzed allylic nucleophilic substitution.

Original language	English
Pages (from-to)	1556-1558
Number of pages	3
Journal	Chemical Communications
Issue number	15
DOIs	https://doi.org/10.1039/b617871e
Publication status	Published - Feb 2007

Keywords

ASYMMETRIC HYDROGENATION
DNA
CATALYSIS
ENZYMES
CHEMISTRY
EVOLUTION
RNA

Access to Document

10.1039/b617871e

Cite this

@article{aedfe7f4cd6d4af3ac0c80aa3aafa068,

title = "Phosphine containing oligonucleotides for the development of metallodeoxyribozymes",

abstract = "Novel transition metal catalysts based on oligonucleotides can be easily obtained by functionalization of 5-iodouridine with phosphine ligands, resulting in good asymmetric induction in palladium catalyzed allylic nucleophilic substitution.",

keywords = "ASYMMETRIC HYDROGENATION, DNA, CATALYSIS, ENZYMES, CHEMISTRY, EVOLUTION, RNA",

author = "Loic Ropartz and Meeuwenoord, {Nico J.} and {van der Marel}, {Gijsbert A.} and {van Leeuwen}, {Piet W. N. M.} and Slawin, {Alexandra M. Z.} and Kamer, {Paul C. J.}",

year = "2007",

month = feb,

doi = "10.1039/b617871e",

language = "English",

pages = "1556--1558",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "15",

}

TY - JOUR

T1 - Phosphine containing oligonucleotides for the development of metallodeoxyribozymes

AU - Ropartz, Loic

AU - Meeuwenoord, Nico J.

AU - van der Marel, Gijsbert A.

AU - van Leeuwen, Piet W. N. M.

AU - Slawin, Alexandra M. Z.

AU - Kamer, Paul C. J.

PY - 2007/2

Y1 - 2007/2

N2 - Novel transition metal catalysts based on oligonucleotides can be easily obtained by functionalization of 5-iodouridine with phosphine ligands, resulting in good asymmetric induction in palladium catalyzed allylic nucleophilic substitution.

AB - Novel transition metal catalysts based on oligonucleotides can be easily obtained by functionalization of 5-iodouridine with phosphine ligands, resulting in good asymmetric induction in palladium catalyzed allylic nucleophilic substitution.

KW - ASYMMETRIC HYDROGENATION

KW - DNA

KW - CATALYSIS

KW - ENZYMES

KW - CHEMISTRY

KW - EVOLUTION

KW - RNA

UR - http://www.scopus.com/inward/record.url?scp=34147133199&partnerID=8YFLogxK

UR - http://www.rsc.org/Publishing/Journals/CC/article.asp?doi=b617871e

U2 - 10.1039/b617871e

DO - 10.1039/b617871e

M3 - Article

SN - 1359-7345

SP - 1556

EP - 1558

JO - Chemical Communications

JF - Chemical Communications

IS - 15

ER -

Phosphine containing oligonucleotides for the development of metallodeoxyribozymes

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this