Phasic responses in dorsal raphe serotonin neurons to noxious stimuli

J. V. Schweimer, M. A. Ungless*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

69 Citations (Scopus)

Abstract

Serotonin is widely implicated in aversive processing. It is not clear, however, whether serotonin neurons encode information about aversive stimuli. We found that, in the dorsal raphe of anesthetized rats, most neurochemically-identified clocklike serotonin neurons were phasically excited by noxious footshocks, whereas most bursting serotonin neurons were inhibited. These results suggest that discrete groups of serotonin neurons differentially code for aversive stimuli.

Original languageEnglish
Pages (from-to)1209-1215
Number of pages7
JournalNeuroscience
Volume171
Issue number4
DOIs
Publication statusPublished - 29 Dec 2010

Keywords

  • Aversive
  • Basal ganglia
  • Dopamine
  • Midbrain
  • Punishment

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