Abstract
The new well-defined catalyst [Pd(mu-Cl)Cl(IPr*)](2) enables the efficient Grignard reagent cross-coupling for the synthesis of tetra-ortho-substituted biaryls. The high reactivity of the complex is associated with the important bulkiness of the IPr* ligand. The dimer represents the most efficient catalyst reported to date for this challenging transformation.
Original language | English |
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Pages (from-to) | 5586-5589 |
Number of pages | 4 |
Journal | Organic & Biomolecular Chemistry |
Volume | 12 |
Issue number | 30 |
DOIs | |
Publication status | Published - 14 Aug 2014 |
Keywords
- N-HETEROCYCLIC CARBENE
- SUZUKI-MIYAURA COUPLINGS
- ARYL CHLORIDES
- LIGANDS
- COORDINATION
- FLEXIBILITY
- COMPLEXES
- HALIDES
- NHC