[Pd(IPr*(acac)Cl]: An Easily Synthesized, Bulky Precatalyst for C-N Bond Formation

Sebastien Meiries, Anthony Chartoire, Alexandra M. Z. Slawin, Steven P. Nolan

Research output: Contribution to journalArticlepeer-review

65 Citations (Scopus)

Abstract

A very straightforward synthesis of [Pd(IPr*)(acac)Cl] has been developed from commercially available Pd(acac)(2) and the easily prepared IPr*center dot HCl (acac = acetylacetonate; IPr* = N,N'-bis(2,6-bis(diphenylmethyl)-4-methylphenyl)imidazol-2-ylidene). The reactivity of the resulting complex [Pd(IPr*)(acac)Cl] (1) as a highly active Pd-II precatalyst for the Buchwald-Hartwig arylamination coupling has been explored. A wide range of substrates with varying electronic and steric demands of both coupling partners has been screened successfully. The chemoselectivity of the reaction was also explored by using aryl heterodihalides.

Original languageEnglish
Pages (from-to)3402-3409
Number of pages8
JournalOrganometallics
Volume31
Issue number8
DOIs
Publication statusPublished - 23 Apr 2012

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