Palladium catalysed elaboration of codeine and morphine

S. G. Davies; C. J. Goodwin; D. Pyatt; A. D. Smith

doi:10.1039/b102581n

Palladium catalysed elaboration of codeine and morphine

S. G. Davies^*
, C. J. Goodwin
, D. Pyatt
, A. D. Smith

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Palladium catalysed coupling reactions of 6-O-tert-butyldimethylsilyl-1-bromocodeine and 6-O-tert-butyldimethylsilyl-3-trifluoromethylsulfonylmorphine allow a range of substituted analogues of codeine in the 1-position and morphine in the 3-position to be efficiently and selectively prepared.

Original language	English
Pages (from-to)	1413-1420
Number of pages	8
Journal	Journal of the Chemical Society. Perkin Transactions 1
Issue number	12
DOIs	https://doi.org/10.1039/b102581n
Publication status	Published - 1 Jan 2001

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title = "Palladium catalysed elaboration of codeine and morphine",

abstract = "Palladium catalysed coupling reactions of 6-O-tert-butyldimethylsilyl-1-bromocodeine and 6-O-tert-butyldimethylsilyl-3-trifluoromethylsulfonylmorphine allow a range of substituted analogues of codeine in the 1-position and morphine in the 3-position to be efficiently and selectively prepared.",

author = "Davies, \{S. G.\} and Goodwin, \{C. J.\} and D. Pyatt and Smith, \{A. D.\}",

year = "2001",

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doi = "10.1039/b102581n",

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AU - Goodwin, C. J.

AU - Pyatt, D.

AU - Smith, A. D.

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Y1 - 2001/1/1

N2 - Palladium catalysed coupling reactions of 6-O-tert-butyldimethylsilyl-1-bromocodeine and 6-O-tert-butyldimethylsilyl-3-trifluoromethylsulfonylmorphine allow a range of substituted analogues of codeine in the 1-position and morphine in the 3-position to be efficiently and selectively prepared.

AB - Palladium catalysed coupling reactions of 6-O-tert-butyldimethylsilyl-1-bromocodeine and 6-O-tert-butyldimethylsilyl-3-trifluoromethylsulfonylmorphine allow a range of substituted analogues of codeine in the 1-position and morphine in the 3-position to be efficiently and selectively prepared.

UR - https://www.scopus.com/pages/publications/0034743047

U2 - 10.1039/b102581n

DO - 10.1039/b102581n

M3 - Article

AN - SCOPUS:0034743047

SN - 1472-7781

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EP - 1420

JO - Journal of the Chemical Society. Perkin Transactions 1

JF - Journal of the Chemical Society. Perkin Transactions 1

IS - 12

ER -

Palladium catalysed elaboration of codeine and morphine

Abstract

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