Oxazoles

R Alan Aitken; Ryan A. Inwood

doi:10.1016/B978-0-12-818655-8.00157-8

Oxazoles

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Developments in the chemistry of five-membered ring heterocycles containing non-adjacent oxygen and nitrogen atoms in the period 2007–2020 are reviewed. Application of theoretical and structural methods to these compounds is described including X-ray structure determination. The reactions and ring synthesis of oxazoles, oxazolines, oxazolidines and oxazolidinones are discussed in detail with the synthetic routes categorised according to the source of the ring atoms. Applications are dominated by the development of new chiral oxazoline ligands for metal-promoted asymmetric reactions and an extensive listing of these is provided together with several other important applications in the medicinal, polymer and photophysics areas.

Original language	English
Title of host publication	Comprehensive heterocyclic chemistry IV - a review of the literature 2008-2021
Subtitle of host publication	Volume 4: Five-membered rings with two heteroatoms, and their fused carbocyclic derivatives
Editors	R. A. Aitken
Place of Publication	Amsterdam
Publisher	Elsevier (incl. Pergamon )
Chapter	4.04
Pages	435-481
Number of pages	47
ISBN (Electronic)	9780128186565
ISBN (Print)	9780323912679, 9780128186558
DOIs	https://doi.org/10.1016/B978-0-12-818655-8.00157-8
Publication status	Published - 23 Nov 2021

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10.1016/B978-0-12-818655-8.00157-8

Cite this

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title = "Oxazoles",

abstract = "Developments in the chemistry of five-membered ring heterocycles containing non-adjacent oxygen and nitrogen atoms in the period 2007–2020 are reviewed. Application of theoretical and structural methods to these compounds is described including X-ray structure determination. The reactions and ring synthesis of oxazoles, oxazolines, oxazolidines and oxazolidinones are discussed in detail with the synthetic routes categorised according to the source of the ring atoms. Applications are dominated by the development of new chiral oxazoline ligands for metal-promoted asymmetric reactions and an extensive listing of these is provided together with several other important applications in the medicinal, polymer and photophysics areas.",

author = "Aitken, {R Alan} and Inwood, {Ryan A.}",

year = "2021",

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TY - CHAP

T1 - Oxazoles

AU - Aitken, R Alan

AU - Inwood, Ryan A.

PY - 2021/11/23

Y1 - 2021/11/23

N2 - Developments in the chemistry of five-membered ring heterocycles containing non-adjacent oxygen and nitrogen atoms in the period 2007–2020 are reviewed. Application of theoretical and structural methods to these compounds is described including X-ray structure determination. The reactions and ring synthesis of oxazoles, oxazolines, oxazolidines and oxazolidinones are discussed in detail with the synthetic routes categorised according to the source of the ring atoms. Applications are dominated by the development of new chiral oxazoline ligands for metal-promoted asymmetric reactions and an extensive listing of these is provided together with several other important applications in the medicinal, polymer and photophysics areas.

AB - Developments in the chemistry of five-membered ring heterocycles containing non-adjacent oxygen and nitrogen atoms in the period 2007–2020 are reviewed. Application of theoretical and structural methods to these compounds is described including X-ray structure determination. The reactions and ring synthesis of oxazoles, oxazolines, oxazolidines and oxazolidinones are discussed in detail with the synthetic routes categorised according to the source of the ring atoms. Applications are dominated by the development of new chiral oxazoline ligands for metal-promoted asymmetric reactions and an extensive listing of these is provided together with several other important applications in the medicinal, polymer and photophysics areas.

UR - https://doi.org/10.1016/c2013-1-23160-9

UR - https://discover.libraryhub.jisc.ac.uk/search?isn=9780128186558&rn=1

U2 - 10.1016/B978-0-12-818655-8.00157-8

DO - 10.1016/B978-0-12-818655-8.00157-8

M3 - Chapter

SN - 9780323912679

SN - 9780128186558

SP - 435

EP - 481

BT - Comprehensive heterocyclic chemistry IV - a review of the literature 2008-2021

A2 - Aitken, R. A.

PB - Elsevier (incl. Pergamon )

CY - Amsterdam

ER -

Oxazoles

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Comprehensive heterocyclic chemistry IV - a review of the literature 2008-2021: Volume 4: Five-membered rings with two heteroatoms, and their fused carbocyclic derivatives

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Oxazoles

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Comprehensive heterocyclic chemistry IV - a review of the literature 2008-2021: Volume 4: Five-membered rings with two heteroatoms, and their fused carbocyclic derivatives

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