Ovarian function and fertility preservation for young people treated for cancer

Soline Caprioli; Tom Kelsey; W Hamish B Wallace

doi:10.1007/978-3-030-47767-7_3

Ovarian function and fertility preservation for young people treated for cancer

Soline Caprioli
, Tom Kelsey
, W Hamish B Wallace

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Further advances in the treatment of young people with cancer have led to improved survival, with 85.6% 5-year relative survival for ages 0–14 in the USA for the years 2010–2016 [18]. However, successful cancer treatment during childhood can cause infertility and premature ovarian insufficiency (POI) in some patients [20, 33]. The risk of developing POI is dependent on a number of factors, which include the nature of the underlying disease and the planned therapy. Both chemotherapy and radiotherapy have been shown to affect ovarian function either directly by depleting the primordial follicle pool or indirectly via effects on hormonal regulation of ovarian function.

Original language	English
Title of host publication	Female and male fertility preservation
Editors	Michael Grynberg, Pasquale Patrizio
Place of Publication	Cham
Publisher	Springer
Pages	35-45
ISBN (Electronic)	9783030477677
ISBN (Print)	9783030477660, 9783030477691
DOIs	https://doi.org/10.1007/978-3-030-47767-7_3
Publication status	Published - 1 Jan 2022

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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Caprioli_2021_OvarianFunction_Chapter_AAM
Copyright © Springer Nature Switzerland AG 2022. This work has been made available online in accordance with publisher policies or with permission. Permission for further reuse of this content should be sought from the publisher or the rights holder. This is the author created accepted manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at https://doi.org/10.1007/978-3-030-47767-7_3
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ER -

Ovarian function and fertility preservation for young people treated for cancer

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