Observations on antigenic relatedness between viruses of the herpes simplex 'neutroseron'

R. A. Killington; R. E. Randall; J. Yeo; R. W. Honess; I. W. Halliburton; D. H. Watson

Observations on antigenic relatedness between viruses of the herpes simplex 'neutroseron'

R. A. Killington, R. E. Randall, J. Yeo, R. W. Honess, I. W. Halliburton, D. H. Watson

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Abstract

The antigenic relatedness of three viruses of the herpes simplex type 1 neutroseron - herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) and bovine mammillitis virus (BMV) - has been examined by immune precipitation and virus neutralization tests. Many virus-specific infected-cell polypeptides were shown to possess antigenic sites shared by both HSV-1 and HSV-2. Cross-neutralization between the viruses is mediated through antibodies to at least two antigenic sites, one shared by HSV-1, HSV-2 and BMV and one shared by HSV-1 and HSV-2 but not BMV.

Original language	English
Pages (from-to)	185-194
Number of pages	10
Journal	IARC (International Agency for Research on Cancer) Scientific Publications
Volume	No. 24
Publication status	Published - 1 Dec 1978

Cite this

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title = "Observations on antigenic relatedness between viruses of the herpes simplex 'neutroseron'",

abstract = "The antigenic relatedness of three viruses of the herpes simplex type 1 neutroseron - herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) and bovine mammillitis virus (BMV) - has been examined by immune precipitation and virus neutralization tests. Many virus-specific infected-cell polypeptides were shown to possess antigenic sites shared by both HSV-1 and HSV-2. Cross-neutralization between the viruses is mediated through antibodies to at least two antigenic sites, one shared by HSV-1, HSV-2 and BMV and one shared by HSV-1 and HSV-2 but not BMV.",

author = "Killington, {R. A.} and Randall, {R. E.} and J. Yeo and Honess, {R. W.} and Halliburton, {I. W.} and Watson, {D. H.}",

year = "1978",

month = dec,

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language = "English",

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AU - Killington, R. A.

AU - Randall, R. E.

AU - Yeo, J.

AU - Honess, R. W.

AU - Halliburton, I. W.

AU - Watson, D. H.

PY - 1978/12/1

Y1 - 1978/12/1

N2 - The antigenic relatedness of three viruses of the herpes simplex type 1 neutroseron - herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) and bovine mammillitis virus (BMV) - has been examined by immune precipitation and virus neutralization tests. Many virus-specific infected-cell polypeptides were shown to possess antigenic sites shared by both HSV-1 and HSV-2. Cross-neutralization between the viruses is mediated through antibodies to at least two antigenic sites, one shared by HSV-1, HSV-2 and BMV and one shared by HSV-1 and HSV-2 but not BMV.

AB - The antigenic relatedness of three viruses of the herpes simplex type 1 neutroseron - herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) and bovine mammillitis virus (BMV) - has been examined by immune precipitation and virus neutralization tests. Many virus-specific infected-cell polypeptides were shown to possess antigenic sites shared by both HSV-1 and HSV-2. Cross-neutralization between the viruses is mediated through antibodies to at least two antigenic sites, one shared by HSV-1, HSV-2 and BMV and one shared by HSV-1 and HSV-2 but not BMV.

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M3 - Article

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AN - SCOPUS:0018225953

VL - No. 24

SP - 185

EP - 194

JO - IARC (International Agency for Research on Cancer) Scientific Publications

JF - IARC (International Agency for Research on Cancer) Scientific Publications

ER -

Observations on antigenic relatedness between viruses of the herpes simplex 'neutroseron'

Abstract

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