Nuclear perturbations following adenovirus infection

W C Russell, D A Matthews

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Abstract

Adenoviruses are processed and assembled in the nuclei of infected cells and thereby produce significant perturbations to their structure and function. As the complex interactions that occur in the nuclei of uninfected cells are not yet fully understood many of the changes seen on infection have been described mainly in morphological terms. This chapter attempts to place more recent findings into this context and demonstrates that adenoviruses are able to hijack many cellular processes and enzymes to their advantage. in particular, modifications to nuclear PODS and nucleoli have more recently been explored in greater detail.

Original languageEnglish
Title of host publicationAdenoviruses: model and vectors in virus host interactions: virion-structure, viral replication and host-cell interactions
EditorsW. Dörfler, P. Böhm
PublisherSpringer
Pages399-413
Number of pages15
ISBN (Print)3-540-00154-9
Publication statusPublished - 2003

Publication series

NameCurrent topics in microbiology and immunology
Volume272
ISSN (Print)0070-217X

Keywords

  • CORE PROTEIN-V
  • HELA-CELLS
  • IN-VITRO
  • ELECTRON-MICROSCOPE
  • DNA-REPLICATION
  • COILED BODIES
  • PORE COMPLEX
  • PML BODIES
  • VIRAL-DNA
  • VIRUS

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