Non-tuberculous mycobacterial pulmonary disease (NTM-PD): epidemiology, diagnosis and multidisciplinary management

Kartik Kumar; Aravind Ponnuswamy; Toby GD Capstick; Christabelle Chen; Douglas McCabe; Rhys Hurst; Lisa Morrison; Fiona Moore; Matt Gallardo; Jennie Keane; Shirley Harwood; Tanya Sinnett; Sarah Bryant; Ronan Breen; Onn Min Kon; Marc Lipman; Michael R Loebinger; Devesh J Dhasmana

doi:10.1016/j.clinme.2024.100017

Non-tuberculous mycobacterial pulmonary disease (NTM-PD): epidemiology, diagnosis and multidisciplinary management

Kartik Kumar, Aravind Ponnuswamy, Toby GD Capstick, Christabelle Chen, Douglas McCabe, Rhys Hurst, Lisa Morrison, Fiona Moore, Matt Gallardo, Jennie Keane, Shirley Harwood, Tanya Sinnett, Sarah Bryant, Ronan Breen, Onn Min Kon, Marc Lipman, Michael R Loebinger, Devesh J Dhasmana^*

^*Corresponding author for this work

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Non-tuberculous mycobacteria (NTM) are ubiquitous environmental organisms that can cause significant disease in both immunocompromised and immunocompetent individuals. The incidence of NTM pulmonary disease (NTM-PD) is rising globally. Diagnostic challenges persist and treatment efficacy is variable. This article provides an overview of NTM-PD for clinicians. We discuss how common it is, who is at risk, how it is diagnosed and the multidisciplinary approach to its clinical management.

Original language	English
Article number	100017
Number of pages	8
Journal	Clinical Medicine
Volume	24
Issue number	1
Early online date	17 Jan 2024
DOIs	https://doi.org/10.1016/j.clinme.2024.100017
Publication status	Published - 21 Feb 2024

Keywords

Humans
Nontuberculous Mycobacteria
Non-tuberculous mycobacteria
Pulmonary disease
Multidisciplinary management
Diagnosis
Epidemiology
Immunocompromised Host

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10.1016/j.clinme.2024.100017Licence: CC BY-NC-ND

Kumar_2024_CM_Non-TB_CC
Copyright © 2024 The Authors. Published by Elsevier Ltd on behalf of Royal College of Physicians. This is an open access article under the CC BY-NC-ND license ( http://creativecommons.org/licenses/by-nc-nd/4.0/ ).
Final published version, 1.81 MBLicence: CC BY-NC-ND

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Kumar, K., Ponnuswamy, A., Capstick, T. GD., Chen, C., McCabe, D., Hurst, R., Morrison, L., Moore, F., Gallardo, M., Keane, J., Harwood, S., Sinnett, T., Bryant, S., Breen, R., Kon, O. M., Lipman, M., Loebinger, M. R., & Dhasmana, D. J. (2024). Non-tuberculous mycobacterial pulmonary disease (NTM-PD): epidemiology, diagnosis and multidisciplinary management. Clinical Medicine, 24(1), Article 100017. https://doi.org/10.1016/j.clinme.2024.100017

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title = "Non-tuberculous mycobacterial pulmonary disease (NTM-PD): epidemiology, diagnosis and multidisciplinary management",

abstract = "Non-tuberculous mycobacteria (NTM) are ubiquitous environmental organisms that can cause significant disease in both immunocompromised and immunocompetent individuals. The incidence of NTM pulmonary disease (NTM-PD) is rising globally. Diagnostic challenges persist and treatment efficacy is variable. This article provides an overview of NTM-PD for clinicians. We discuss how common it is, who is at risk, how it is diagnosed and the multidisciplinary approach to its clinical management.",

keywords = "Humans, Nontuberculous Mycobacteria, Non-tuberculous mycobacteria, Pulmonary disease, Multidisciplinary management, Diagnosis, Epidemiology, Immunocompromised Host",

author = "Kartik Kumar and Aravind Ponnuswamy and Capstick, \{Toby GD\} and Christabelle Chen and Douglas McCabe and Rhys Hurst and Lisa Morrison and Fiona Moore and Matt Gallardo and Jennie Keane and Shirley Harwood and Tanya Sinnett and Sarah Bryant and Ronan Breen and Kon, \{Onn Min\} and Marc Lipman and Loebinger, \{Michael R\} and Dhasmana, \{Devesh J\}",

note = "Kartik Kumar was supported by the National Institute for Health and Care Research (NIHR) Imperial Biomedical Research Centre (BRC).",

year = "2024",

month = feb,

day = "21",

doi = "10.1016/j.clinme.2024.100017",

language = "English",

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Kumar, K, Ponnuswamy, A, Capstick, TGD, Chen, C, McCabe, D, Hurst, R, Morrison, L, Moore, F, Gallardo, M, Keane, J, Harwood, S, Sinnett, T, Bryant, S, Breen, R, Kon, OM, Lipman, M, Loebinger, MR & Dhasmana, DJ 2024, 'Non-tuberculous mycobacterial pulmonary disease (NTM-PD): epidemiology, diagnosis and multidisciplinary management', Clinical Medicine, vol. 24, no. 1, 100017. https://doi.org/10.1016/j.clinme.2024.100017

TY - JOUR

T1 - Non-tuberculous mycobacterial pulmonary disease (NTM-PD)

T2 - epidemiology, diagnosis and multidisciplinary management

AU - Kumar, Kartik

AU - Ponnuswamy, Aravind

AU - Capstick, Toby GD

AU - Chen, Christabelle

AU - McCabe, Douglas

AU - Hurst, Rhys

AU - Morrison, Lisa

AU - Moore, Fiona

AU - Gallardo, Matt

AU - Keane, Jennie

AU - Harwood, Shirley

AU - Sinnett, Tanya

AU - Bryant, Sarah

AU - Breen, Ronan

AU - Kon, Onn Min

AU - Lipman, Marc

AU - Loebinger, Michael R

AU - Dhasmana, Devesh J

N1 - Kartik Kumar was supported by the National Institute for Health and Care Research (NIHR) Imperial Biomedical Research Centre (BRC).

PY - 2024/2/21

Y1 - 2024/2/21

N2 - Non-tuberculous mycobacteria (NTM) are ubiquitous environmental organisms that can cause significant disease in both immunocompromised and immunocompetent individuals. The incidence of NTM pulmonary disease (NTM-PD) is rising globally. Diagnostic challenges persist and treatment efficacy is variable. This article provides an overview of NTM-PD for clinicians. We discuss how common it is, who is at risk, how it is diagnosed and the multidisciplinary approach to its clinical management.

AB - Non-tuberculous mycobacteria (NTM) are ubiquitous environmental organisms that can cause significant disease in both immunocompromised and immunocompetent individuals. The incidence of NTM pulmonary disease (NTM-PD) is rising globally. Diagnostic challenges persist and treatment efficacy is variable. This article provides an overview of NTM-PD for clinicians. We discuss how common it is, who is at risk, how it is diagnosed and the multidisciplinary approach to its clinical management.

KW - Humans

KW - Nontuberculous Mycobacteria

KW - Non-tuberculous mycobacteria

KW - Pulmonary disease

KW - Multidisciplinary management

KW - Diagnosis

KW - Epidemiology

KW - Immunocompromised Host

UR - https://www.scopus.com/pages/publications/85185792555

U2 - 10.1016/j.clinme.2024.100017

DO - 10.1016/j.clinme.2024.100017

M3 - Article

C2 - 38387207

SN - 1470-2118

VL - 24

JO - Clinical Medicine

JF - Clinical Medicine

IS - 1

M1 - 100017

ER -

Non-tuberculous mycobacterial pulmonary disease (NTM-PD): epidemiology, diagnosis and multidisciplinary management

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Keywords

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