New pacidamycins biosynthetically: probing N- and C-terminal substrate specificity

Amany E. Ragab; Sabine Grueschow; Emma J. Rackham; Rebecca J. M. Goss

doi:10.1039/c003964k

New pacidamycins biosynthetically: probing N- and C-terminal substrate specificity

Amany E. Ragab, Sabine Grueschow, Emma J. Rackham, Rebecca J. M. Goss^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Feeding phenylalanine analogues to Streptomyces coeruleorubidus reveals the remarkable steric and electronic flexibility of this biosynthetic pathway and leads to the generation of a series of new halopacidamycins.

Original language	English
Pages (from-to)	3128-3129
Number of pages	2
Journal	Organic & Biomolecular Chemistry
Volume	8
Issue number	14
DOIs	https://doi.org/10.1039/c003964k
Publication status	Published - 2010

Keywords

SERIES
PSEUDOMONAS-AERUGINOSA ACTIVITY
ANTIBIOTICS

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@article{ebe667c62fc8487ba0dfbf7cfb0e85e2,

title = "New pacidamycins biosynthetically: probing N- and C-terminal substrate specificity",

abstract = "Feeding phenylalanine analogues to Streptomyces coeruleorubidus reveals the remarkable steric and electronic flexibility of this biosynthetic pathway and leads to the generation of a series of new halopacidamycins.",

keywords = "SERIES, PSEUDOMONAS-AERUGINOSA ACTIVITY, ANTIBIOTICS",

author = "Ragab, {Amany E.} and Sabine Grueschow and Rackham, {Emma J.} and Goss, {Rebecca J. M.}",

year = "2010",

doi = "10.1039/c003964k",

language = "English",

volume = "8",

pages = "3128--3129",

journal = "Organic & Biomolecular Chemistry",

issn = "1477-0520",

publisher = "Royal Society of Chemistry",

number = "14",

}

TY - JOUR

T1 - New pacidamycins biosynthetically: probing N- and C-terminal substrate specificity

AU - Ragab, Amany E.

AU - Grueschow, Sabine

AU - Rackham, Emma J.

AU - Goss, Rebecca J. M.

PY - 2010

Y1 - 2010

N2 - Feeding phenylalanine analogues to Streptomyces coeruleorubidus reveals the remarkable steric and electronic flexibility of this biosynthetic pathway and leads to the generation of a series of new halopacidamycins.

AB - Feeding phenylalanine analogues to Streptomyces coeruleorubidus reveals the remarkable steric and electronic flexibility of this biosynthetic pathway and leads to the generation of a series of new halopacidamycins.

KW - SERIES

KW - PSEUDOMONAS-AERUGINOSA ACTIVITY

KW - ANTIBIOTICS

U2 - 10.1039/c003964k

DO - 10.1039/c003964k

M3 - Article

SN - 1477-0520

VL - 8

SP - 3128

EP - 3129

JO - Organic & Biomolecular Chemistry

JF - Organic & Biomolecular Chemistry

IS - 14

ER -

New pacidamycins biosynthetically: probing N- and C-terminal substrate specificity

Abstract

Keywords

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