New pacidamycins biosynthetically: probing N- and C-terminal substrate specificity

Amany E. Ragab, Sabine Grueschow, Emma J. Rackham, Rebecca J. M. Goss*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

Feeding phenylalanine analogues to Streptomyces coeruleorubidus reveals the remarkable steric and electronic flexibility of this biosynthetic pathway and leads to the generation of a series of new halopacidamycins.

Original languageEnglish
Pages (from-to)3128-3129
Number of pages2
JournalOrganic & Biomolecular Chemistry
Volume8
Issue number14
DOIs
Publication statusPublished - 2010

Keywords

  • SERIES
  • PSEUDOMONAS-AERUGINOSA ACTIVITY
  • ANTIBIOTICS

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