New Insights into the Mechanism of Enzymatic Chlorination of Tryptophan

Silvana Flecks; Eugenio R. Patallo; Xiaofeng Zhu; Aliz J. Ernyei; Gotthard Seifert; Alexander Schneider; Changjiang Dong; Janies H. Naismith; Karl-Heinz van Pee

doi:10.1002/anie.200802466

New Insights into the Mechanism of Enzymatic Chlorination of Tryptophan

Silvana Flecks
, Eugenio R. Patallo
, Xiaofeng Zhu
, Aliz J. Ernyei
, Gotthard Seifert
, Alexander Schneider
, Changjiang Dong
, Janies H. Naismith
, Karl-Heinz van Pee

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	9533-9536
Number of pages	4
Journal	Angewandte Chemie International Edition
Volume	47
DOIs	https://doi.org/10.1002/anie.200802466
Publication status	Published - 2008

Keywords

enzymatic halogenation
flavin-dependent
hypochlorous acid
reaction mechanism
tryptophan halogenase
PSEUDOMONAS-FLUORESCENS
7-HALOGENASE PRNA
BIOSYNTHESIS
PROTEIN
PYRROLNITRIN

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10.1002/anie.200802466

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@article{e72f9f9359ae449690e06d7bd59fdc18,

title = "New Insights into the Mechanism of Enzymatic Chlorination of Tryptophan",

keywords = "enzymatic halogenation, flavin-dependent, hypochlorous acid, reaction mechanism, tryptophan halogenase, PSEUDOMONAS-FLUORESCENS, 7-HALOGENASE PRNA, BIOSYNTHESIS, PROTEIN, PYRROLNITRIN",

author = "Silvana Flecks and Patallo, \{Eugenio R.\} and Xiaofeng Zhu and Ernyei, \{Aliz J.\} and Gotthard Seifert and Alexander Schneider and Changjiang Dong and Naismith, \{Janies H.\} and \{van Pee\}, Karl-Heinz",

year = "2008",

doi = "10.1002/anie.200802466",

language = "English",

volume = "47",

pages = "9533--9536",

journal = "Angewandte Chemie International Edition",

issn = "1433-7851",

publisher = "John Wiley \& Sons, Ltd",

}

TY - JOUR

T1 - New Insights into the Mechanism of Enzymatic Chlorination of Tryptophan

AU - Flecks, Silvana

AU - Patallo, Eugenio R.

AU - Zhu, Xiaofeng

AU - Ernyei, Aliz J.

AU - Seifert, Gotthard

AU - Schneider, Alexander

AU - Dong, Changjiang

AU - Naismith, Janies H.

AU - van Pee, Karl-Heinz

PY - 2008

Y1 - 2008

KW - enzymatic halogenation

KW - flavin-dependent

KW - hypochlorous acid

KW - reaction mechanism

KW - tryptophan halogenase

KW - PSEUDOMONAS-FLUORESCENS

KW - 7-HALOGENASE PRNA

KW - BIOSYNTHESIS

KW - PROTEIN

KW - PYRROLNITRIN

UR - https://www.scopus.com/pages/publications/56749090818

U2 - 10.1002/anie.200802466

DO - 10.1002/anie.200802466

M3 - Article

SN - 1433-7851

VL - 47

SP - 9533

EP - 9536

JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition

ER -

New Insights into the Mechanism of Enzymatic Chlorination of Tryptophan

Keywords

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bb/c000080/1: The pyrrolnitrin biosynthetic pathway

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New Insights into the Mechanism of Enzymatic Chlorination of Tryptophan

Keywords

Access to Document

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Projects

bb/c000080/1: The pyrrolnitrin biosynthetic pathway

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