New Insights into the Mechanism of Enzymatic Chlorination of Tryptophan

Silvana Flecks; Eugenio R. Patallo; Xiaofeng Zhu; Aliz J. Ernyei; Gotthard Seifert; Alexander Schneider; Changjiang Dong; Janies H. Naismith; Karl-Heinz van Pee

doi:10.1002/anie.200802466

New Insights into the Mechanism of Enzymatic Chlorination of Tryptophan

Silvana Flecks, Eugenio R. Patallo, Xiaofeng Zhu, Aliz J. Ernyei, Gotthard Seifert, Alexander Schneider, Changjiang Dong, Janies H. Naismith, Karl-Heinz van Pee

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	9533-9536
Number of pages	4
Journal	Angewandte Chemie International Edition
Volume	47
DOIs	https://doi.org/10.1002/anie.200802466
Publication status	Published - 2008

Keywords

enzymatic halogenation
flavin-dependent
hypochlorous acid
reaction mechanism
tryptophan halogenase
PSEUDOMONAS-FLUORESCENS
7-HALOGENASE PRNA
BIOSYNTHESIS
PROTEIN
PYRROLNITRIN

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10.1002/anie.200802466

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@article{e72f9f9359ae449690e06d7bd59fdc18,

title = "New Insights into the Mechanism of Enzymatic Chlorination of Tryptophan",

keywords = "enzymatic halogenation, flavin-dependent, hypochlorous acid, reaction mechanism, tryptophan halogenase, PSEUDOMONAS-FLUORESCENS, 7-HALOGENASE PRNA, BIOSYNTHESIS, PROTEIN, PYRROLNITRIN",

author = "Silvana Flecks and Patallo, {Eugenio R.} and Xiaofeng Zhu and Ernyei, {Aliz J.} and Gotthard Seifert and Alexander Schneider and Changjiang Dong and Naismith, {Janies H.} and {van Pee}, Karl-Heinz",

year = "2008",

doi = "10.1002/anie.200802466",

language = "English",

volume = "47",

pages = "9533--9536",

journal = "Angewandte Chemie International Edition",

issn = "1433-7851",

publisher = "John Wiley & Sons, Ltd",

}

TY - JOUR

T1 - New Insights into the Mechanism of Enzymatic Chlorination of Tryptophan

AU - Flecks, Silvana

AU - Patallo, Eugenio R.

AU - Zhu, Xiaofeng

AU - Ernyei, Aliz J.

AU - Seifert, Gotthard

AU - Schneider, Alexander

AU - Dong, Changjiang

AU - Naismith, Janies H.

AU - van Pee, Karl-Heinz

PY - 2008

Y1 - 2008

KW - enzymatic halogenation

KW - flavin-dependent

KW - hypochlorous acid

KW - reaction mechanism

KW - tryptophan halogenase

KW - PSEUDOMONAS-FLUORESCENS

KW - 7-HALOGENASE PRNA

KW - BIOSYNTHESIS

KW - PROTEIN

KW - PYRROLNITRIN

UR - http://www.scopus.com/inward/record.url?scp=56749090818&partnerID=8YFLogxK

U2 - 10.1002/anie.200802466

DO - 10.1002/anie.200802466

M3 - Article

SN - 1433-7851

VL - 47

SP - 9533

EP - 9536

JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition

ER -

New Insights into the Mechanism of Enzymatic Chlorination of Tryptophan

Keywords

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bb/c000080/1: The pyrrolnitrin biosynthetic pathway

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New Insights into the Mechanism of Enzymatic Chlorination of Tryptophan

Keywords

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bb/c000080/1: The pyrrolnitrin biosynthetic pathway

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