Abstract
As well as regulating neuronal survival, neurotrophins control the growth of axons and dendrites. New light has been shed on the mechanism of this latter control process by the discovery that the common neurotrophin receptor p75(NTR) interacts in a ligand-dependent manner with RhoA, a known regulator of actin assembly.
Original language | English |
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Number of pages | 3 |
Journal | Current Biology |
Volume | 10 |
Publication status | Published - 9 Mar 2000 |
Keywords
- DEVELOPING SENSORY NEURONS
- RECEPTOR
- P75
- INNERVATION
- OUTGROWTH
- P75(NTR)
- SURVIVAL
- PROMOTE
- BINDING
- NGF