Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance

Jose R. Bayascas, Stephan Wullschleger, Kei Sakamoto, Juan M. Garcia-Martinez, Carol Clacher, David Komander, Daan M. F. van Aalten, Krishna M. Boini, Florian Lang, Christopher Lipina, Lisa Logie, Calum Sutherland, John A. Chudek, Janna A. van Diepen, Peter J. Voshol, John Milton Lucocq, Dario R. Alessi

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Biochemistry, Genetics and Molecular Biology