Multiple-Quantum Cross-Polarization and Two-Dimensional MQMAS NMR of Quadrupolar Nuclei

Cross-polarization from H-1 to the multiple-quantum coherences of a quadrupolar nucleus is used in combination with the two-dimensional multiple-quantum magic angle spinning (MQMAS) NMR experiment in order to extract high-resolution CPMAS NMR spectra. The technique is demonstrated on Na-23 (S = 3/2), O-17, Al-27 (both S = 5/2), and Sc-45 (S = 7/2) nuclei, showing the applicability of multiple-quantum cross-polarization to systems with differing spin quantum number, gyromagnetic ratio, and relative nuclide abundance. The utility of this two-dimensional MAS NMR experiment for spectral editing and site-specific measurement of crosspolarization intensities is demonstrated. The possibility of direct cross-polarization to higher order multiple-quantum coherences is also considered and three-, five-, and seven-quantum cross-polarized Sc-45 MAS NMR spectra are presented. (C) 2000 Academic Press.