TY - JOUR
T1 - Monolithic integration of microfluidic channels and semiconductor lasers
AU - Cran-McGreehin, S J
AU - Dholakia, Kishan
AU - Krauss, Thomas Fraser
PY - 2006/8/21
Y1 - 2006/8/21
N2 - We present a fabrication method for the monolithic integration of microfluidic channels into semiconductor laser material. Lasers are designed to couple directly into the microfluidic channel, allowing submerged particles pass through the output beams of the lasers. The interaction between particles in the channel and the lasers, operated in either forward or reverse bias, allows for particle detection, and the optical forces can be used to trap and move particles. Both interrogation and manipulation are made more amenable for lab-on-a-chip applications through monolithic integration. The devices are very small, they require no external optical components, have perfect intrinsic alignment, and can be created with virtually any planar configuration of lasers in order to perform a variety of tasks. Their operation requires no optical expertise and only low electrical power, thus making them suitable for computer interfacing and automation. Insulating the pn junctions from the fluid is the key challenge, which is overcome by using photo-definable SU8-2000 polymer. (c) Optical Society of America.
AB - We present a fabrication method for the monolithic integration of microfluidic channels into semiconductor laser material. Lasers are designed to couple directly into the microfluidic channel, allowing submerged particles pass through the output beams of the lasers. The interaction between particles in the channel and the lasers, operated in either forward or reverse bias, allows for particle detection, and the optical forces can be used to trap and move particles. Both interrogation and manipulation are made more amenable for lab-on-a-chip applications through monolithic integration. The devices are very small, they require no external optical components, have perfect intrinsic alignment, and can be created with virtually any planar configuration of lasers in order to perform a variety of tasks. Their operation requires no optical expertise and only low electrical power, thus making them suitable for computer interfacing and automation. Insulating the pn junctions from the fluid is the key challenge, which is overcome by using photo-definable SU8-2000 polymer. (c) Optical Society of America.
KW - SINGLE CELLS
UR - http://www.scopus.com/inward/record.url?scp=33747748170&partnerID=8YFLogxK
UR - http://www.opticsinfobase.org/abstract.cfm?URI=oe-14-17-7723
M3 - Article
SN - 1094-4087
VL - 14
SP - 7723
JO - Optics Express
JF - Optics Express
IS - 17
ER -