Monoamine oxidases: to inhibit or not to inhibit.

R. R. Ramsay*, M. B. Gravestock

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

40 Citations (Scopus)

Abstract

Monoamine oxidase (MAO) inhibitors were developed as antidepressants but many drugs, including the novel oxazolidinone antibacterial agents, share similar molecular properties and have MAO inhibitory activity. Factors important for binding antidepressants and modifications to decrease binding of oxazolidinones to avoid undesirable vascular effects are discussed.

Original languageEnglish
Pages (from-to)129-136
Number of pages8
JournalMini reviews in medicinal chemistry
Volume3
Issue number2
DOIs
Publication statusPublished - 1 Jan 2003

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