Molecular basis for trehalase inhibition revealed by the structure of trehalase in complex with potent inhibitors

Robert P. Gibson, Tracey M. Gloster, Shirley Roberts, R. Anthony J. Warren, Isabel Storch de Gracia, Angela Garcia, Jose L. Chiara, Gideon J. Davies

Research output: Contribution to journalArticlepeer-review

95 Citations (Scopus)
Original languageEnglish
Pages (from-to)4115-4119
Number of pages5
JournalAngewandte Chemie International Edition
Volume46
Issue number22
DOIs
Publication statusPublished - 2007

Keywords

  • inhibitors
  • protein structures
  • trehalases
  • trehazolins
  • validoxylamines
  • NAG-THIAZOLINE
  • PHOSPHORYLASE
  • DERIVATIVES
  • HYDROLYSIS
  • REFINEMENT
  • RESOLUTION
  • CHEMISTRY
  • PLANTS

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