Molecular Basis for beta-Glucosidase Inhibition by Ring-Modified Calystegine Analogues

Matilde Aguilar, Tracey M. Gloster, M. Isabel Garcia-Moreno, Carmen Ortiz Mellet, Gideon J. Davies, Amadeu Llebaria, Josefina Casas, Meritxell Egido-Gabas, Jose M. Garcia Fernandez

Research output: Contribution to journalArticlepeer-review

38 Citations (Scopus)
Original languageEnglish
Pages (from-to)2612-2618
Number of pages7
JournalChemBioChem
Volume9
Issue number16
DOIs
Publication statusPublished - 3 Nov 2008

Keywords

  • azasugars
  • calystegines
  • glucosidases
  • iminosugars
  • inhibitors
  • GLYCOSIDASE INHIBITORS
  • BIOLOGICAL-ACTIVITY
  • PHARMACOLOGICAL CHAPERONES
  • IMINOSUGAR DERIVATIVES
  • GAUCHERS-DISEASE
  • HIGHLY POTENT
  • B-2 ANALOGS
  • GLUCOCEREBROSIDASE
  • BINDING
  • DESIGN

Cite this