Modifiying NEMO

R T  Hay

doi:10.1038/ncb0204-89

Modifiying NEMO

R T Hay

School of Biology

Research output: Contribution to journal › Editorial › peer-review

Abstract

Genotoxic stress induces a survival response by releasing the transcription factor NF-kappaB from its inhibitor IkappaBalpha. In response to DNA damage, this initially requires the nuclear modification of the IkappaB kinase regulator NEMO/IKKgamma. by SUMO and ubiquitin.

Original language	English
Pages (from-to)	89-91
Number of pages	4
Journal	Nature Cell Biology
Volume	6
DOIs	https://doi.org/10.1038/ncb0204-89
Publication status	Published - Feb 2004

Keywords

KAPPA-B ACTIVATION
ECTODERMAL DYSPLASIA
SUMO-1
UBIQUITIN
NUCLEAR
ATM

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10.1038/ncb0204-89

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title = "Modifiying NEMO",

abstract = "Genotoxic stress induces a survival response by releasing the transcription factor NF-kappaB from its inhibitor IkappaBalpha. In response to DNA damage, this initially requires the nuclear modification of the IkappaB kinase regulator NEMO/IKKgamma. by SUMO and ubiquitin.",

keywords = "KAPPA-B ACTIVATION, ECTODERMAL DYSPLASIA, SUMO-1, UBIQUITIN, NUCLEAR, ATM",

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year = "2004",

month = feb,

doi = "10.1038/ncb0204-89",

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AU - Hay, R T

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AB - Genotoxic stress induces a survival response by releasing the transcription factor NF-kappaB from its inhibitor IkappaBalpha. In response to DNA damage, this initially requires the nuclear modification of the IkappaB kinase regulator NEMO/IKKgamma. by SUMO and ubiquitin.

KW - KAPPA-B ACTIVATION

KW - ECTODERMAL DYSPLASIA

KW - SUMO-1

KW - UBIQUITIN

KW - NUCLEAR

KW - ATM

UR - https://www.scopus.com/pages/publications/1842538832

U2 - 10.1038/ncb0204-89

DO - 10.1038/ncb0204-89

M3 - Editorial

SN - 1476-4679

VL - 6

SP - 89

EP - 91

JO - Nature Cell Biology

JF - Nature Cell Biology

ER -

Modifiying NEMO

Abstract

Keywords

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