Abstract
Genotoxic stress induces a survival response by releasing the transcription factor NF-kappaB from its inhibitor IkappaBalpha. In response to DNA damage, this initially requires the nuclear modification of the IkappaB kinase regulator NEMO/IKKgamma. by SUMO and ubiquitin.
Original language | English |
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Pages (from-to) | 89-91 |
Number of pages | 4 |
Journal | Nature Cell Biology |
Volume | 6 |
DOIs | |
Publication status | Published - Feb 2004 |
Keywords
- KAPPA-B ACTIVATION
- ECTODERMAL DYSPLASIA
- SUMO-1
- UBIQUITIN
- NUCLEAR
- ATM