Microlaser-based contractility sensing in single cardiomyocytes and whole hearts

Marcel Schubert*, Lewis Woolfson, Isla R.M. Barnard, Andrew Morton, Becky Casement, Gavin B. Robertson, Gareth B. Miles, Samantha J. Pitt, Carl S. Tucker, Malte C. Gather

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Abstract

Microscopic whispering gallery mode lasers detect minute changes in cellular refractive index inside individual cardiac cells and in live zebrafish. We show that these signals encode cardiac contractility that can be used for intravital sensing.

Original languageEnglish
Title of host publicationNovel biophotonics techniques and applications V
EditorsArjen Amelink, Seemantini K. Nadkarni
PublisherSPIE
Number of pages3
ISBN (Electronic)9781510628434
DOIs
Publication statusPublished - 22 Jul 2019
EventEuropean Conferences on Biomedical Optics - Munich, Germany
Duration: 23 Jun 201927 Jun 2019

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume11075
ISSN (Print)1605-7422

Conference

ConferenceEuropean Conferences on Biomedical Optics
Country/TerritoryGermany
CityMunich
Period23/06/1927/06/19

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