Metal-organic frameworks as potential multi-carriers of drugs

Sara Rojas; Paul S. Wheatley; Elsa Quartapelle-Procopio; Barbara Gil; Bartosz Marszalek; Russell E. Morris; Elisa Barea

doi:10.1039/c3ce41289j

Metal-organic frameworks as potential multi-carriers of drugs

Sara Rojas^*, Paul S. Wheatley, Elsa Quartapelle-Procopio, Barbara Gil, Bartosz Marszalek, Russell E. Morris, Elisa Barea

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

The metal-organic framework CPO-27-Ni is presented as a proof-of-concept model for the incorporation and release of two non-conventional anticancer drugs: [Ru(p-cymene)Cl-2(pta)] (RAPTA-C) and NO.

Original language	English
Pages (from-to)	9364-9367
Number of pages	4
Journal	CrystEngComm
Volume	15
Issue number	45
DOIs	https://doi.org/10.1039/c3ce41289j
Publication status	Published - 2013

Keywords

NITRIC-OXIDE
COORDINATION POLYMER
HYDROGEN ADSORPTION
IN-VITRO
RELEASE
NO
COMPOUND
DELIVERY
SITES
CELLS

Access to Document

10.1039/c3ce41289j

Assembly Disassembly Reassembly: Assembly disassembly reassembly - New routes to extended structures and their impact
Morris, R. E. (PI)
EPSRC
1/08/13 → 31/07/18
Project: Fellowship
Hemilabile switchable metal-organic: Hemilabile and switchable metal-organic frameworks
Morris, R. E. (PI)
EPSRC
1/03/13 → 28/02/16
Project: Standard
Non-classic Crystal Growth: Non-classic Crystal Growth and New Catalysts
Zhou, W. (PI)
British Council
1/12/12 → 31/12/14
Project: Standard

Cite this

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title = "Metal-organic frameworks as potential multi-carriers of drugs",

abstract = "The metal-organic framework CPO-27-Ni is presented as a proof-of-concept model for the incorporation and release of two non-conventional anticancer drugs: [Ru(p-cymene)Cl-2(pta)] (RAPTA-C) and NO.",

keywords = "NITRIC-OXIDE, COORDINATION POLYMER, HYDROGEN ADSORPTION, IN-VITRO, RELEASE, NO, COMPOUND, DELIVERY, SITES, CELLS",

author = "Sara Rojas and Wheatley, {Paul S.} and Elsa Quartapelle-Procopio and Barbara Gil and Bartosz Marszalek and Morris, {Russell E.} and Elisa Barea",

year = "2013",

doi = "10.1039/c3ce41289j",

language = "English",

volume = "15",

pages = "9364--9367",

journal = "CrystEngComm",

issn = "1466-8033",

publisher = "ROYAL SOC CHEMISTRY",

number = "45",

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T1 - Metal-organic frameworks as potential multi-carriers of drugs

AU - Rojas, Sara

AU - Wheatley, Paul S.

AU - Quartapelle-Procopio, Elsa

AU - Gil, Barbara

AU - Marszalek, Bartosz

AU - Morris, Russell E.

AU - Barea, Elisa

PY - 2013

Y1 - 2013

N2 - The metal-organic framework CPO-27-Ni is presented as a proof-of-concept model for the incorporation and release of two non-conventional anticancer drugs: [Ru(p-cymene)Cl-2(pta)] (RAPTA-C) and NO.

AB - The metal-organic framework CPO-27-Ni is presented as a proof-of-concept model for the incorporation and release of two non-conventional anticancer drugs: [Ru(p-cymene)Cl-2(pta)] (RAPTA-C) and NO.

KW - NITRIC-OXIDE

KW - COORDINATION POLYMER

KW - HYDROGEN ADSORPTION

KW - IN-VITRO

KW - RELEASE

KW - NO

KW - COMPOUND

KW - DELIVERY

KW - SITES

KW - CELLS

U2 - 10.1039/c3ce41289j

DO - 10.1039/c3ce41289j

M3 - Article

SN - 1466-8033

VL - 15

SP - 9364

EP - 9367

JO - CrystEngComm

JF - CrystEngComm

IS - 45

ER -

Metal-organic frameworks as potential multi-carriers of drugs

Abstract

Keywords

Access to Document

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Projects

Assembly Disassembly Reassembly: Assembly disassembly reassembly - New routes to extended structures and their impact

Hemilabile switchable metal-organic: Hemilabile and switchable metal-organic frameworks

Non-classic Crystal Growth: Non-classic Crystal Growth and New Catalysts

Cite this