Mechanistic Insights into Water Activation in SAM Hydroxide Adenosyltransferase (duf-62)

Hai Deng; Stephen A. McMahon; Alessandra S. Eustaquio; Bradley S. Moore; James Henderson Naismith; David O'Hagan

doi:10.1002/cbic.200900369

Mechanistic Insights into Water Activation in SAM Hydroxide Adenosyltransferase (duf-62)

Hai Deng, Stephen A. McMahon, Alessandra S. Eustaquio, Bradley S. Moore, James Henderson Naismith, David O'Hagan

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Original language	English
Pages (from-to)	2455-2459
Number of pages	5
Journal	ChemBioChem
Volume	10
Issue number	15
Early online date	8 Sept 2009
DOIs	https://doi.org/10.1002/cbic.200900369
Publication status	Published - 12 Oct 2009

Keywords

biosynthesis
catalysis
enzyme catalysis
enzymes
MACROMOLECULAR STRUCTURES
CATALYTIC MECHANISM
CRYSTAL-STRUCTURE
BACTERIAL
SYNTHASE
ENZYME
REFINEMENT
FLUORINASE
CHLORINASE

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10.1002/cbic.200900369

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@article{ff6723996fae411ea7aa6472e62f0788,

title = "Mechanistic Insights into Water Activation in SAM Hydroxide Adenosyltransferase (duf-62)",

keywords = "biosynthesis, catalysis, enzyme catalysis, enzymes, MACROMOLECULAR STRUCTURES, CATALYTIC MECHANISM, CRYSTAL-STRUCTURE, BACTERIAL, SYNTHASE, ENZYME, REFINEMENT, FLUORINASE, CHLORINASE",

author = "Hai Deng and McMahon, {Stephen A.} and Eustaquio, {Alessandra S.} and Moore, {Bradley S.} and Naismith, {James Henderson} and David O'Hagan",

year = "2009",

month = oct,

day = "12",

doi = "10.1002/cbic.200900369",

language = "English",

volume = "10",

pages = "2455--2459",

journal = "ChemBioChem",

issn = "1439-4227",

publisher = "John Wiley & Sons, Ltd",

number = "15",

}

TY - JOUR

T1 - Mechanistic Insights into Water Activation in SAM Hydroxide Adenosyltransferase (duf-62)

AU - Deng, Hai

AU - McMahon, Stephen A.

AU - Eustaquio, Alessandra S.

AU - Moore, Bradley S.

AU - Naismith, James Henderson

AU - O'Hagan, David

PY - 2009/10/12

Y1 - 2009/10/12

KW - biosynthesis

KW - catalysis

KW - enzyme catalysis

KW - enzymes

KW - MACROMOLECULAR STRUCTURES

KW - CATALYTIC MECHANISM

KW - CRYSTAL-STRUCTURE

KW - BACTERIAL

KW - SYNTHASE

KW - ENZYME

KW - REFINEMENT

KW - FLUORINASE

KW - CHLORINASE

UR - http://www.scopus.com/inward/record.url?scp=71049171266&partnerID=8YFLogxK

UR - http://ukpmc.ac.uk/abstract/MED/19739191

U2 - 10.1002/cbic.200900369

DO - 10.1002/cbic.200900369

M3 - Article

SN - 1439-4227

VL - 10

SP - 2455

EP - 2459

JO - ChemBioChem

JF - ChemBioChem

IS - 15

ER -

Mechanistic Insights into Water Activation in SAM Hydroxide Adenosyltransferase (duf-62)

Keywords

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Enzymatic fluorination in Streptomyces: Enzymatic Fluorination in Streptomyces cattleya. Setting a framework for biotechnological development

BBSRC BBS/B/14442: TRANSFER - Structural proteomics; targeting biosynthetic pathways, pathogenesis and DNA processing

BBSRC BBS/B/14426: SPORT

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Mechanistic Insights into Water Activation in SAM Hydroxide Adenosyltransferase (duf-62)

Keywords

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Projects

Enzymatic fluorination in Streptomyces: Enzymatic Fluorination in Streptomyces cattleya. Setting a framework for biotechnological development

BBSRC BBS/B/14442: TRANSFER - Structural proteomics; targeting biosynthetic pathways, pathogenesis and DNA processing

BBSRC BBS/B/14426: SPORT

Cite this