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Mechanism of the neurotoxicity of MPTP. An update
Thomas P. Singer
*
, Rona R. Ramsay
*
Corresponding author for this work
Biomedical Sciences Research Complex
School of Biology
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Biochemistry, Genetics and Molecular Biology
Alkylation
50%
Binding Site
50%
Glial Cells
50%
Inner Membrane
50%
Microglia
50%
Monoamine Oxidase A
50%
Monoamine Oxidase B
50%
NADH Dehydrogenase
100%
Rotenone
50%
Pharmacology, Toxicology and Pharmaceutical Science
1 Methyl 4 Phenylpyridinium
80%
1,2,3,6 Tetrahydro 1 Methyl 4 Phenylpyridine
100%
Amine Oxidase (Flavin Containing) Isoenzyme A
20%
Amine Oxidase (Flavin Containing) Isoenzyme B
40%
Binding Site
20%
Molecular Target
20%
Neurotoxicity
100%
Oxidoreductase
40%
Rotenone
20%
Tetraphenylboron
20%
Neuroscience
Alkylation
20%
Binding Site
20%
Inner Membrane
20%
Microglia
20%
Monoamine Oxidase A
20%
Monoamine Oxidase B
20%
MPP+
80%
Neurotoxicity
100%
Rotenone
20%
Tetrahydropyridine
100%