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Mechanism of the neurotoxicity of MPTP. An update
Thomas P. Singer
*
, Rona R. Ramsay
*
Corresponding author for this work
Biomedical Sciences Research Complex
School of Biology
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Biochemistry, Genetics and Molecular Biology
NADH Dehydrogenase
100%
Alkylation
50%
Glial Cells
50%
Monoamine Oxidase A
50%
Binding Site
50%
Monoamine Oxidase B
50%
Inner Membrane
50%
Microglia
50%
Rotenone
50%
Dopamine
50%
Chemistry
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
100%
Neurotoxicity
100%
Neurotoxic
60%
Monoamine
40%
NADH
40%
Biochemicals
40%
Binding Site
20%
Ion Pair
20%
Pyridine Ring
20%
Alkylation
20%
Rotenone
20%
Dopamine
20%