Measurement of proteinuria

Anne-Marie Côté, Ashalata Mallapur, Geetanjali Katageri, Umesh Ramdurg, Shashidhar Bannale, Li Wang, Laura A Magee, Suellen Miller, William Stones

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Citations (Scopus)

Abstract

In pregnancy, there is a focus on measurement of proteinuria as it has been regarded as critical to the diagnosis of pre-eclampsia, the most dangerous of the hypertensive disorders of pregnancy. However, it is increasingly recognised that proteinuria is not essential for the diagnosis of pre-eclampsia, which can be based on other end-organ complications (such as elevated liver enzymes). Although heavy proteinuria has been linked with an increased risk of stillbirth in a ‘signs and symptoms only’ model of maternal risk (i.e., miniPIERS), we lack the ability to identify a level of proteinuria above which maternal and/or perinatal risk is heightened. Therefore, at present, we rely on the detection of proteinuria that exceeds what is normally excreted by healthy pregnant women. Proteinuria detection methods are also a matter of keen debate, with all available methods having advantages and disadvantages.
Original languageEnglish
Title of host publicationThe FIGO Textbook of Pregnancy Hypertension
Subtitle of host publicationAn evidence-based guide to monitoring, prevention and management
EditorsLaura A Magee, Peter von Dadelszen, William Stones, Matthews Mathai
Place of PublicationLondon
PublisherThe Global Library of Women’s Medicine
Pages19-32
ISBN (Print)9780992754556
Publication statusPublished - 2016

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