MDR/XDRTB: What are the new treatment options?

Research output: Contribution to journalReview articlepeer-review


Concerns are increasing that the drugs we have used to treat this chronic pulmonary infection will cease to work because of development of resistance, raising the threat of untreatable disease. This review explains the molecular and clinical basis of resistance. The current best practice for the treatment of multi-drug resistance is described. There are a number of new drugs and regimens currently under investigation and these are described. The importance of improved case finding, diagnosis and early treatment are emphasised.

Original languageEnglish
Pages (from-to)211-216
Number of pages6
JournalCurrent Respiratory Medicine Reviews
Issue number3
Publication statusPublished - 27 Nov 2013


  • Antibiotic resistance
  • Drug treatment
  • Extremely drug resistant
  • Multidrug resistance
  • Tuberculosis


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