Low Temperature Capture of Pseudorotaxanes

Nurul Izzaty Hassan; Vicente del Amo; Ewen Calder; Douglas Philp

doi:10.1021/ol1027915

Low Temperature Capture of Pseudorotaxanes

Nurul Izzaty Hassan, Vicente del Amo, Ewen Calder, Douglas Philp

Research output: Contribution to journal › Article › peer-review

Abstract

Yields of a rotaxane can be improved by employing a two-step capture protocol. Cooling a solution of the linear and macrocyclic components required for the rotaxane increases the population of the target pseudorotaxane, which is then captured by a rapid capping reaction between an azide and PPh3. The resulting iminophosphorane rotaxane can then be manipulated synthetically at elevated temperatures.

Original language	English
Pages (from-to)	458-461
Number of pages	4
Journal	Organic Letters
Volume	13
Issue number	3
DOIs	https://doi.org/10.1021/ol1027915
Publication status	Published - 4 Feb 2011

Keywords

MOLECULAR INFORMATION RATCHET
TEMPLATE SYNTHESIS
ROTAXANES
CHEMISTRY
NETWORKS
SWITCHES
SHUTTLE

Access to Document

10.1021/ol1027915

EPSRC: PROBING CROSSCATALYSIS: Probing Crosscatalysis, Autocatalysis and Amplific
Philp, D. (PI)
EPSRC
1/01/07 → 31/07/10
Project: Standard

Cite this

@article{bac3a7246f244d83b97fe7e01a5ef09a,

title = "Low Temperature Capture of Pseudorotaxanes",

abstract = "Yields of a rotaxane can be improved by employing a two-step capture protocol. Cooling a solution of the linear and macrocyclic components required for the rotaxane increases the population of the target pseudorotaxane, which is then captured by a rapid capping reaction between an azide and PPh3. The resulting iminophosphorane rotaxane can then be manipulated synthetically at elevated temperatures.",

keywords = "MOLECULAR INFORMATION RATCHET, TEMPLATE SYNTHESIS, ROTAXANES, CHEMISTRY, NETWORKS, SWITCHES, SHUTTLE",

author = "Hassan, {Nurul Izzaty} and {del Amo}, Vicente and Ewen Calder and Douglas Philp",

year = "2011",

month = feb,

day = "4",

doi = "10.1021/ol1027915",

language = "English",

volume = "13",

pages = "458--461",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society (ACS)",

number = "3",

}

TY - JOUR

T1 - Low Temperature Capture of Pseudorotaxanes

AU - Hassan, Nurul Izzaty

AU - del Amo, Vicente

AU - Calder, Ewen

AU - Philp, Douglas

PY - 2011/2/4

Y1 - 2011/2/4

N2 - Yields of a rotaxane can be improved by employing a two-step capture protocol. Cooling a solution of the linear and macrocyclic components required for the rotaxane increases the population of the target pseudorotaxane, which is then captured by a rapid capping reaction between an azide and PPh3. The resulting iminophosphorane rotaxane can then be manipulated synthetically at elevated temperatures.

AB - Yields of a rotaxane can be improved by employing a two-step capture protocol. Cooling a solution of the linear and macrocyclic components required for the rotaxane increases the population of the target pseudorotaxane, which is then captured by a rapid capping reaction between an azide and PPh3. The resulting iminophosphorane rotaxane can then be manipulated synthetically at elevated temperatures.

KW - MOLECULAR INFORMATION RATCHET

KW - TEMPLATE SYNTHESIS

KW - ROTAXANES

KW - CHEMISTRY

KW - NETWORKS

KW - SWITCHES

KW - SHUTTLE

U2 - 10.1021/ol1027915

DO - 10.1021/ol1027915

M3 - Article

SN - 1523-7060

VL - 13

SP - 458

EP - 461

JO - Organic Letters

JF - Organic Letters

IS - 3

ER -

Low Temperature Capture of Pseudorotaxanes

Abstract

Keywords

Access to Document

Fingerprint

Projects

EPSRC: PROBING CROSSCATALYSIS: Probing Crosscatalysis, Autocatalysis and Amplific

Cite this