Low cost, patterning of human hNT brain cells on parylene-C with UV & IR laser machining

Brad J. Raos; C. P. Unsworth; J. L. Costa; C. A. Rohde; C. S. Doyle; E. Delivopoulos; A. F. Murray; M. E. Dickinson; M. C. Simpson; E. S. Graham; A. S. Bunting

doi:10.1109/EMBC.2013.6609637

Low cost, patterning of human hNT brain cells on parylene-C with UV & IR laser machining

Brad J. Raos, C. P. Unsworth, J. L. Costa, C. A. Rohde, C. S. Doyle, E. Delivopoulos, A. F. Murray, M. E. Dickinson, M. C. Simpson, E. S. Graham, A. S. Bunting

School of Physics and Astronomy

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

This paper describes the use of 800nm femtosecond infrared (IR) and 248nm nanosecond ultraviolet (UV) laser radiation in performing ablative micromachining of parylene-C on SiO₂ substrates for the patterning of human hNT astrocytes. Results are presented that support the validity of using IR laser ablative micromachining for patterning human hNT astrocytes cells while UV laser radiation produces photo-oxidation of the parylene-C and destroys cell patterning. The findings demonstrate how IR laser ablative micromachining of parylene-C on SiO₂ substrates can offer a low cost, accessible alternative for rapid prototyping, high yield cell patterning.

Original language	English
Title of host publication	2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Pages	862-865
Number of pages	4
DOIs	https://doi.org/10.1109/EMBC.2013.6609637
Publication status	Published - 31 Oct 2013
Event	2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 - Osaka, Japan Duration: 3 Jul 2013 → 7 Jul 2013

Conference

Conference	2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Country/Territory	Japan
City	Osaka
Period	3/07/13 → 7/07/13

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Raos, B. J., Unsworth, C. P., Costa, J. L., Rohde, C. A., Doyle, C. S., Delivopoulos, E., Murray, A. F., Dickinson, M. E., Simpson, M. C., Graham, E. S., & Bunting, A. S. (2013). Low cost, patterning of human hNT brain cells on parylene-C with UV & IR laser machining. In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 (pp. 862-865). Article 6609637 https://doi.org/10.1109/EMBC.2013.6609637

@inproceedings{767668bf04634297bf42dad51f53613b,

title = "Low cost, patterning of human hNT brain cells on parylene-C with UV & IR laser machining",

abstract = "This paper describes the use of 800nm femtosecond infrared (IR) and 248nm nanosecond ultraviolet (UV) laser radiation in performing ablative micromachining of parylene-C on SiO2 substrates for the patterning of human hNT astrocytes. Results are presented that support the validity of using IR laser ablative micromachining for patterning human hNT astrocytes cells while UV laser radiation produces photo-oxidation of the parylene-C and destroys cell patterning. The findings demonstrate how IR laser ablative micromachining of parylene-C on SiO2 substrates can offer a low cost, accessible alternative for rapid prototyping, high yield cell patterning.",

author = "Raos, {Brad J.} and Unsworth, {C. P.} and Costa, {J. L.} and Rohde, {C. A.} and Doyle, {C. S.} and E. Delivopoulos and Murray, {A. F.} and Dickinson, {M. E.} and Simpson, {M. C.} and Graham, {E. S.} and Bunting, {A. S.}",

year = "2013",

month = oct,

day = "31",

doi = "10.1109/EMBC.2013.6609637",

language = "English",

isbn = "9781457702167",

pages = "862--865",

booktitle = "2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013",

note = "2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 ; Conference date: 03-07-2013 Through 07-07-2013",

}

Raos, BJ, Unsworth, CP, Costa, JL, Rohde, CA, Doyle, CS, Delivopoulos, E, Murray, AF, Dickinson, ME, Simpson, MC, Graham, ES & Bunting, AS 2013, Low cost, patterning of human hNT brain cells on parylene-C with UV & IR laser machining. in 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013., 6609637, pp. 862-865, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013, Osaka, Japan, 3/07/13. https://doi.org/10.1109/EMBC.2013.6609637

TY - GEN

T1 - Low cost, patterning of human hNT brain cells on parylene-C with UV & IR laser machining

AU - Raos, Brad J.

AU - Unsworth, C. P.

AU - Costa, J. L.

AU - Rohde, C. A.

AU - Doyle, C. S.

AU - Delivopoulos, E.

AU - Murray, A. F.

AU - Dickinson, M. E.

AU - Simpson, M. C.

AU - Graham, E. S.

AU - Bunting, A. S.

PY - 2013/10/31

Y1 - 2013/10/31

N2 - This paper describes the use of 800nm femtosecond infrared (IR) and 248nm nanosecond ultraviolet (UV) laser radiation in performing ablative micromachining of parylene-C on SiO2 substrates for the patterning of human hNT astrocytes. Results are presented that support the validity of using IR laser ablative micromachining for patterning human hNT astrocytes cells while UV laser radiation produces photo-oxidation of the parylene-C and destroys cell patterning. The findings demonstrate how IR laser ablative micromachining of parylene-C on SiO2 substrates can offer a low cost, accessible alternative for rapid prototyping, high yield cell patterning.

AB - This paper describes the use of 800nm femtosecond infrared (IR) and 248nm nanosecond ultraviolet (UV) laser radiation in performing ablative micromachining of parylene-C on SiO2 substrates for the patterning of human hNT astrocytes. Results are presented that support the validity of using IR laser ablative micromachining for patterning human hNT astrocytes cells while UV laser radiation produces photo-oxidation of the parylene-C and destroys cell patterning. The findings demonstrate how IR laser ablative micromachining of parylene-C on SiO2 substrates can offer a low cost, accessible alternative for rapid prototyping, high yield cell patterning.

U2 - 10.1109/EMBC.2013.6609637

DO - 10.1109/EMBC.2013.6609637

M3 - Conference contribution

C2 - 24109824

AN - SCOPUS:84886490054

SN - 9781457702167

SP - 862

EP - 865

BT - 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013

T2 - 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013

Y2 - 3 July 2013 through 7 July 2013

ER -

Low cost, patterning of human hNT brain cells on parylene-C with UV & IR laser machining

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