Light-stable silver N-Heterocyclic carbene catalysts for the alkynylation of ketones in air

Faima Lazreg; Mathieu Lesieur; Andrew J.  Sansom; Catherine S.J. Cazin

doi:10.1002/cctc.201500869

Light-stable silver N-Heterocyclic carbene catalysts for the alkynylation of ketones in air

Faima Lazreg, Mathieu Lesieur, Andrew J. Sansom, Catherine S.J. Cazin

Research output: Contribution to journal › Article › peer-review

Abstract

N-Heterocyclic carbene (NHC) silver(I) complexes were efficiently employed in the alkynylation of ketones. These cationic complexes were found highly active and efficient under mild conditions without the need of additive, and in air. The mechanism of this transformation was investigated. Experiments suggest the formation of a silver-acetylide key intermediate and the release of one ligand from the silver centre enabling the transformation.

Original language	English
Journal	ChemCatChem
Volume	In press
Early online date	10 Nov 2015
DOIs	https://doi.org/10.1002/cctc.201500869
Publication status	Published - 2015

Keywords

Alkynes
Carbene ligands
Copper
Ketones
SIlver

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10.1002/cctc.201500869

Cazin_2015_CCC_LightSilver_AM
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This work is made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at https://dx.doi.org/10.1002/cctc.201500869
Accepted author manuscript, 592 KB

Cite this

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title = "Light-stable silver N-Heterocyclic carbene catalysts for the alkynylation of ketones in air",

abstract = "N-Heterocyclic carbene (NHC) silver(I) complexes were efficiently employed in the alkynylation of ketones. These cationic complexes were found highly active and efficient under mild conditions without the need of additive, and in air. The mechanism of this transformation was investigated. Experiments suggest the formation of a silver-acetylide key intermediate and the release of one ligand from the silver centre enabling the transformation.",

keywords = "Alkynes, Carbene ligands, Copper, Ketones, SIlver",

author = "Faima Lazreg and Mathieu Lesieur and Sansom, {Andrew J.} and Cazin, {Catherine S.J.}",

note = "The authors gratefully acknowledge the Royal Society (University Research Fellowship to C.S.J.C) for funding. ",

year = "2015",

doi = "10.1002/cctc.201500869",

language = "English",

volume = "In press",

journal = "ChemCatChem",

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publisher = "John Wiley & Sons, Ltd",

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T1 - Light-stable silver N-Heterocyclic carbene catalysts for the alkynylation of ketones in air

AU - Lazreg, Faima

AU - Lesieur, Mathieu

AU - Sansom, Andrew J.

AU - Cazin, Catherine S.J.

N1 - The authors gratefully acknowledge the Royal Society (University Research Fellowship to C.S.J.C) for funding.

PY - 2015

Y1 - 2015

N2 - N-Heterocyclic carbene (NHC) silver(I) complexes were efficiently employed in the alkynylation of ketones. These cationic complexes were found highly active and efficient under mild conditions without the need of additive, and in air. The mechanism of this transformation was investigated. Experiments suggest the formation of a silver-acetylide key intermediate and the release of one ligand from the silver centre enabling the transformation.

AB - N-Heterocyclic carbene (NHC) silver(I) complexes were efficiently employed in the alkynylation of ketones. These cationic complexes were found highly active and efficient under mild conditions without the need of additive, and in air. The mechanism of this transformation was investigated. Experiments suggest the formation of a silver-acetylide key intermediate and the release of one ligand from the silver centre enabling the transformation.

KW - Alkynes

KW - Carbene ligands

KW - Copper

KW - Ketones

KW - SIlver

UR - http://onlinelibrary.wiley.com/doi/10.1002/cctc.201500869/suppinfo

U2 - 10.1002/cctc.201500869

DO - 10.1002/cctc.201500869

M3 - Article

SN - 1867-3880

VL - In press

JO - ChemCatChem

JF - ChemCatChem

ER -

Light-stable silver N-Heterocyclic carbene catalysts for the alkynylation of ketones in air

Abstract

Keywords

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Catalytic C-H bond functionalisation: Catalytic C-H bond functionalisation

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Light-stable silver N-Heterocyclic carbene catalysts for the alkynylation of ketones in air

Abstract

Keywords

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Other files and links

Fingerprint

Projects

Catalytic C-H bond functionalisation: Catalytic C-H bond functionalisation

Cite this