TY - JOUR
T1 - Light forces the pace: Optical manipulation for Biophotonics
AU - Stevenson, David James
AU - Gunn-Moore, Frank J
AU - Dholakia, Kishan
PY - 2010
Y1 - 2010
N2 - The Biomedical Sciences have benefited immensely from photonics technologies in the last fifty years. This includes the application of minute forces that enable the trapping and manipulation of cells and single molecules. In terms of the area of biophotonics, optical manipulation has made a seminal contribution to our understanding of the dynamics of single molecules and the microrheology of cells. Here we present a review of optical manipulation, emphasising its impact upon the areas of single molecule studies and cell biology, and indicating some of the key experiments in the fields.
AB - The Biomedical Sciences have benefited immensely from photonics technologies in the last fifty years. This includes the application of minute forces that enable the trapping and manipulation of cells and single molecules. In terms of the area of biophotonics, optical manipulation has made a seminal contribution to our understanding of the dynamics of single molecules and the microrheology of cells. Here we present a review of optical manipulation, emphasising its impact upon the areas of single molecule studies and cell biology, and indicating some of the key experiments in the fields.
UR - http://www.scopus.com/inward/record.url?scp=78650526439&partnerID=8YFLogxK
U2 - 10.1117/1.3475958
DO - 10.1117/1.3475958
M3 - Review article
SN - 1083-3668
VL - 15
SP - 415031
EP - 415021
JO - Journal of Biomedical Optics
JF - Journal of Biomedical Optics
IS - 2
ER -