Isothiourea-mediated one-pot synthesis of functionalized pyridines

Daniel Graham Stark; Louis Christian Morrill; Pei-Pei Yeh; Alexandra Martha Zoya Slawin; Timothy J.C. O'Riordan; Andrew David Smith

doi:10.1002/anie.201306786

Isothiourea-mediated one-pot synthesis of functionalized pyridines

Daniel Graham Stark, Louis Christian Morrill, Pei-Pei Yeh, Alexandra Martha Zoya Slawin, Timothy J.C. O'Riordan, Andrew David Smith

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	11642-11646
Number of pages	5
Journal	Angewandte Chemie International Edition
Volume	52
Issue number	44
Early online date	17 Sept 2013
DOIs	https://doi.org/10.1002/anie.201306786
Publication status	Published - 25 Oct 2013

Keywords

cyclization
heterocycles
isothiourea
Lewis base
organocatalysis
BICYCLIC-BETA-LACTONES
DIELS-ALDER CYCLOADDITIONS
CATALYZED ALDOL-LACTONIZATION
PROMOTED BIS-CYCLIZATIONS
ASYMMETRIC-SYNTHESIS
REGIOSELECTIVE SYNTHESIS
SUBSTITUTED PYRIDINES
COUPLING REACTIONS
SULFONYL TRANSFER
NCAL REACTIONS

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10.1002/anie.201306786

Isothiourea-Mediated One-Pot Synthesis of Functionalized Pyridines
© 2013 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Final published version, 786 KB

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@article{48c73e75acb044deb657b0baa9a8d6dc,

title = "Isothiourea-mediated one-pot synthesis of functionalized pyridines",

keywords = "cyclization, heterocycles, isothiourea, Lewis base, organocatalysis, BICYCLIC-BETA-LACTONES, DIELS-ALDER CYCLOADDITIONS, CATALYZED ALDOL-LACTONIZATION, PROMOTED BIS-CYCLIZATIONS, ASYMMETRIC-SYNTHESIS, REGIOSELECTIVE SYNTHESIS, SUBSTITUTED PYRIDINES, COUPLING REACTIONS, SULFONYL TRANSFER, NCAL REACTIONS",

author = "Stark, {Daniel Graham} and Morrill, {Louis Christian} and Pei-Pei Yeh and Slawin, {Alexandra Martha Zoya} and O'Riordan, {Timothy J.C.} and Smith, {Andrew David}",

note = "This work was supported by the Royal Society, Syngenta/EPSRC, The Carnegie Trust for the Universities of Scotland and ERC.",

year = "2013",

month = oct,

day = "25",

doi = "10.1002/anie.201306786",

language = "English",

volume = "52",

pages = "11642--11646",

journal = "Angewandte Chemie International Edition",

issn = "1521-3773",

publisher = "John Wiley & Sons, Ltd",

number = "44",

}

TY - JOUR

T1 - Isothiourea-mediated one-pot synthesis of functionalized pyridines

AU - Stark, Daniel Graham

AU - Morrill, Louis Christian

AU - Yeh, Pei-Pei

AU - Slawin, Alexandra Martha Zoya

AU - O'Riordan, Timothy J.C.

AU - Smith, Andrew David

N1 - This work was supported by the Royal Society, Syngenta/EPSRC, The Carnegie Trust for the Universities of Scotland and ERC.

PY - 2013/10/25

Y1 - 2013/10/25

KW - cyclization

KW - heterocycles

KW - isothiourea

KW - Lewis base

KW - organocatalysis

KW - BICYCLIC-BETA-LACTONES

KW - DIELS-ALDER CYCLOADDITIONS

KW - CATALYZED ALDOL-LACTONIZATION

KW - PROMOTED BIS-CYCLIZATIONS

KW - ASYMMETRIC-SYNTHESIS

KW - REGIOSELECTIVE SYNTHESIS

KW - SUBSTITUTED PYRIDINES

KW - COUPLING REACTIONS

KW - SULFONYL TRANSFER

KW - NCAL REACTIONS

UR - http://onlinelibrary.wiley.com/doi/10.1002/anie.201306786/full

U2 - 10.1002/anie.201306786

DO - 10.1002/anie.201306786

M3 - Article

SN - 1521-3773

VL - 52

SP - 11642

EP - 11646

JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition

IS - 44

ER -

Isothiourea-mediated one-pot synthesis of functionalized pyridines

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ERC Starting Grant EnolCat: Emulating nature: Reaction diversity and understanding through asymmetric catalysis

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Isothiourea-mediated one-pot synthesis of functionalized pyridines

Keywords

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ERC Starting Grant EnolCat: Emulating nature: Reaction diversity and understanding through asymmetric catalysis

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