Is there a relationship between attention deficit hyperactivity disorder and bipolar disorder?

Lindsey Kent, N Craddock

Research output: Contribution to journalArticlepeer-review

96 Citations (Scopus)

Abstract

With the increasing recognition of attention deficit hyperactivity disorder (ADHD) in adults and psychotic disorders in children and adolescents, the possiblity of a relationship between bipolar disorder (BP) and ADHD has attracted growing interest. This paper critically reviews the scientific literature concerning this postulated relationship by examining evidence from clinico-epidemiological, follow up, family and laboratory studies, including neuroimaging, neuropsychology and genetic studies. The evidence suggests that although the diagnostic categories of BP and ADHD appear to be unrelated, there is support for a possible relationship between some ADHD and manic-like symptoms. However, several fundamental methodological issues require rectification in future research in order to further elucidate the relationship between these disorders. (C) 2003 Elsevier Science B.V. All rights reserved.

Original languageEnglish
Pages (from-to)211-221
Number of pages11
JournalJournal of Affective Disorders
Volume73
Publication statusPublished - Feb 2003

Keywords

  • DOPAMINE TRANSPORTER POLYMORPHISM
  • DEFICIT/HYPERACTIVITY DISORDER
  • NEUROPSYCHOLOGICAL FUNCTION
  • PREPUBERTAL CHILDREN
  • ADOLESCENT MANIA
  • RECEPTOR GENE
  • ONSET MANIA
  • ADHD
  • MRI
  • COMORBIDITY

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