Iron-Sulfur Clusters in Mitochondrial Enzymes

Thomas P. Singer, Rona R. Ramsay

Research output: Chapter in Book/Report/Conference proceedingChapter


The past decade has witnessed an explosive growth in our understanding of the structures and chemical reactivities of the various Fe-S clusters in biological material. These developments have resulted in part from the application of sophisticated physical methods such as EXAFS (extended X-ray absorption fine structure), MCD, Mössbauer, and resonance Raman spectroscopy to the problem. Another advance has come from the development of synthetic analogues of the various Fe-S clusters (Holm, 1977; Ibers and Holm, 1980; Berg and Holm, 1982), and the analysis by X-ray crystallography at high resolution of the structure of the models and of some comparatively simple, low molecular weight proteins containing corresponding clusters.
Original languageEnglish
Title of host publicationThe Enzymes of Biological Membranes: Volume 4 Bioenergetics of Electron and Proton Transport
EditorsAnthony N. Martonosi
Place of PublicationBoston, MA
Number of pages32
ISBN (Print)978-1-4684-4604-3
Publication statusPublished - 1985


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