Iodine-mediated ring closing alkene iodoamination with N-debenzylation for the asymmetric synthesis of polyhydroxylated pyrrolidines

Stephen G. Davies; Rebecca L. Nicholson; Paul D. Price; Paul M. Roberts; Andrew D. Smith

Iodine-mediated ring closing alkene iodoamination with N-debenzylation for the asymmetric synthesis of polyhydroxylated pyrrolidines

Stephen G. Davies^*
, Rebecca L. Nicholson
, Paul D. Price
, Paul M. Roberts
, Andrew D. Smith

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

An iodine-mediated ring closing alkene iodoamination with N-debenzylation protocol provides a direct route for the asymmetric synthesis of polyhydroxylated pyrrolidines from homochiral β-amino acid derivatives.

Original language	English
Pages (from-to)	901-903
Number of pages	3
Journal	Synlett
Issue number	5
Publication status	Published - 2 Apr 2004

Keywords

Conjugate addition
Cyclisation
Debenzylation
Iodoamination
Pyrrolidine

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@article{0f1d9c4d3abd4f16a2fffa7ff5c8c8ce,

title = "Iodine-mediated ring closing alkene iodoamination with N-debenzylation for the asymmetric synthesis of polyhydroxylated pyrrolidines",

abstract = "An iodine-mediated ring closing alkene iodoamination with N-debenzylation protocol provides a direct route for the asymmetric synthesis of polyhydroxylated pyrrolidines from homochiral β-amino acid derivatives.",

keywords = "Conjugate addition, Cyclisation, Debenzylation, Iodoamination, Pyrrolidine",

author = "Davies, \{Stephen G.\} and Nicholson, \{Rebecca L.\} and Price, \{Paul D.\} and Roberts, \{Paul M.\} and Smith, \{Andrew D.\}",

year = "2004",

month = apr,

day = "2",

language = "English",

pages = "901--903",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "5",

}

TY - JOUR

T1 - Iodine-mediated ring closing alkene iodoamination with N-debenzylation for the asymmetric synthesis of polyhydroxylated pyrrolidines

AU - Davies, Stephen G.

AU - Nicholson, Rebecca L.

AU - Price, Paul D.

AU - Roberts, Paul M.

AU - Smith, Andrew D.

PY - 2004/4/2

Y1 - 2004/4/2

N2 - An iodine-mediated ring closing alkene iodoamination with N-debenzylation protocol provides a direct route for the asymmetric synthesis of polyhydroxylated pyrrolidines from homochiral β-amino acid derivatives.

AB - An iodine-mediated ring closing alkene iodoamination with N-debenzylation protocol provides a direct route for the asymmetric synthesis of polyhydroxylated pyrrolidines from homochiral β-amino acid derivatives.

KW - Conjugate addition

KW - Cyclisation

KW - Debenzylation

KW - Iodoamination

KW - Pyrrolidine

UR - https://www.scopus.com/pages/publications/1942489284

M3 - Article

AN - SCOPUS:1942489284

SN - 0936-5214

SP - 901

EP - 903

JO - Synlett

JF - Synlett

IS - 5

ER -

Iodine-mediated ring closing alkene iodoamination with N-debenzylation for the asymmetric synthesis of polyhydroxylated pyrrolidines

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