Iodine-mediated ring closing alkene iodoamination with N-debenzylation for the asymmetric synthesis of polyhydroxylated pyrrolidines

Stephen G. Davies*, Rebecca L. Nicholson, Paul D. Price, Paul M. Roberts, Andrew D. Smith

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

42 Citations (Scopus)

Abstract

An iodine-mediated ring closing alkene iodoamination with N-debenzylation protocol provides a direct route for the asymmetric synthesis of polyhydroxylated pyrrolidines from homochiral β-amino acid derivatives.

Original languageEnglish
Pages (from-to)901-903
Number of pages3
JournalSynlett
Issue number5
Publication statusPublished - 2 Apr 2004

Keywords

  • Conjugate addition
  • Cyclisation
  • Debenzylation
  • Iodoamination
  • Pyrrolidine

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