Interactions between the renin-angiotensin system and catecholamines on the cardiovascular system of elasmobranchs

ML Tierney; K Hamano; G Anderson; Y Takei; K Ashida; Neil Hazon

Interactions between the renin-angiotensin system and catecholamines on the cardiovascular system of elasmobranchs

ML Tierney, K Hamano, G Anderson, Y Takei, K Ashida, Neil Hazon

Research output: Contribution to journal › Article › peer-review

Abstract

The interaction between homologous dogfish angiotensin II ([Asn(1), Pro(3), Ile(5)]-AngII) and catecholamines was examined using blood pressure bioassay. Both noradrenaline and [Asn(1), Pro(3), Ile(5)]-Ang II elicited a presser response. Pre-treatment with phentolamine (1 mg kg(-1)) completely abolished the noradrenaline presser response but did not alter the magnitude of the [Asn(1), Pro(3), Ile(5)]-Ang II presser response although there was an initial delay in the response to [Asn(1), Pro(3), Ile(5)]-Ang II. These results indicate that the Ang II-induced presser response is a direct Ang II-mediated vascular response in elasmobranchs.

Original language	English
Pages (from-to)	333-337
Number of pages	5
Journal	Fish Physiology and Biochemistry
Volume	17
Publication status	Published - Dec 1997

Keywords

elasmobranch
catecholamines
angiotensin II
cardiovascular actions
CONVERTING-ENZYME-INHIBITOR
FISH

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title = "Interactions between the renin-angiotensin system and catecholamines on the cardiovascular system of elasmobranchs",

abstract = "The interaction between homologous dogfish angiotensin II ([Asn(1), Pro(3), Ile(5)]-AngII) and catecholamines was examined using blood pressure bioassay. Both noradrenaline and [Asn(1), Pro(3), Ile(5)]-Ang II elicited a presser response. Pre-treatment with phentolamine (1 mg kg(-1)) completely abolished the noradrenaline presser response but did not alter the magnitude of the [Asn(1), Pro(3), Ile(5)]-Ang II presser response although there was an initial delay in the response to [Asn(1), Pro(3), Ile(5)]-Ang II. These results indicate that the Ang II-induced presser response is a direct Ang II-mediated vascular response in elasmobranchs.",

keywords = "elasmobranch, catecholamines, angiotensin II, cardiovascular actions, CONVERTING-ENZYME-INHIBITOR, FISH",

author = "ML Tierney and K Hamano and G Anderson and Y Takei and K Ashida and Neil Hazon",

year = "1997",

month = dec,

language = "English",

volume = "17",

pages = "333--337",

journal = "Fish Physiology and Biochemistry",

issn = "0920-1742",

publisher = "Springer Science and Business Media B.V.",

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TY - JOUR

T1 - Interactions between the renin-angiotensin system and catecholamines on the cardiovascular system of elasmobranchs

AU - Tierney, ML

AU - Hamano, K

AU - Anderson, G

AU - Takei, Y

AU - Ashida, K

AU - Hazon, Neil

PY - 1997/12

Y1 - 1997/12

N2 - The interaction between homologous dogfish angiotensin II ([Asn(1), Pro(3), Ile(5)]-AngII) and catecholamines was examined using blood pressure bioassay. Both noradrenaline and [Asn(1), Pro(3), Ile(5)]-Ang II elicited a presser response. Pre-treatment with phentolamine (1 mg kg(-1)) completely abolished the noradrenaline presser response but did not alter the magnitude of the [Asn(1), Pro(3), Ile(5)]-Ang II presser response although there was an initial delay in the response to [Asn(1), Pro(3), Ile(5)]-Ang II. These results indicate that the Ang II-induced presser response is a direct Ang II-mediated vascular response in elasmobranchs.

AB - The interaction between homologous dogfish angiotensin II ([Asn(1), Pro(3), Ile(5)]-AngII) and catecholamines was examined using blood pressure bioassay. Both noradrenaline and [Asn(1), Pro(3), Ile(5)]-Ang II elicited a presser response. Pre-treatment with phentolamine (1 mg kg(-1)) completely abolished the noradrenaline presser response but did not alter the magnitude of the [Asn(1), Pro(3), Ile(5)]-Ang II presser response although there was an initial delay in the response to [Asn(1), Pro(3), Ile(5)]-Ang II. These results indicate that the Ang II-induced presser response is a direct Ang II-mediated vascular response in elasmobranchs.

KW - elasmobranch

KW - catecholamines

KW - angiotensin II

KW - cardiovascular actions

KW - CONVERTING-ENZYME-INHIBITOR

KW - FISH

UR - https://www.scopus.com/pages/publications/0001377728

M3 - Article

SN - 0920-1742

VL - 17

SP - 333

EP - 337

JO - Fish Physiology and Biochemistry

JF - Fish Physiology and Biochemistry

ER -

Interactions between the renin-angiotensin system and catecholamines on the cardiovascular system of elasmobranchs

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