Insulin-like growth factor binding proteins of teleost fishes

Daniel Garcia de la Serrana; Daniel J. Macqueen

doi:10.3389/fendo.2018.00080

Insulin-like growth factor binding proteins of teleost fishes

Daniel Garcia de la Serrana, Daniel J. Macqueen

Research output: Contribution to journal › Review article › peer-review

Abstract

The insulin-like growth factor (IGF) binding protein (IGFBP) family has a broad range of physiological functions and a fascinating evolutionary history. This review focuses on the IGFBPs of teleost fishes, where genome duplication events have diversified gene repertoire, function and physiological regulation - with six core IGFBPs expanded into a family of over twenty genes in some lineages. In addition to briefly summarizing the current state of knowledge on teleost IGFBP evolution, function and expression-level regulation, we highlight gaps in our understanding, and promising areas for future work.

Original language	English
Article number	80
Number of pages	12
Journal	Frontiers in Endocrinology
Volume	9
DOIs	https://doi.org/10.3389/fendo.2018.00080
Publication status	Published - 12 Mar 2018

Keywords

Insulin-like growth factor binding protein
Teleost fish
Genome duplication
Physiology
Comparative biology
Gene family evolution

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10.3389/fendo.2018.00080Licence: CC BY

GarciadelaSerrana_2018_FE_TeleostFishes_CC
© 2018 Garcia de la Serrana and Macqueen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Final published version, 1.85 MBLicence: CC BY

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title = "Insulin-like growth factor binding proteins of teleost fishes",

abstract = "The insulin-like growth factor (IGF) binding protein (IGFBP) family has a broad range of physiological functions and a fascinating evolutionary history. This review focuses on the IGFBPs of teleost fishes, where genome duplication events have diversified gene repertoire, function and physiological regulation - with six core IGFBPs expanded into a family of over twenty genes in some lineages. In addition to briefly summarizing the current state of knowledge on teleost IGFBP evolution, function and expression-level regulation, we highlight gaps in our understanding, and promising areas for future work. ",

keywords = "Insulin-like growth factor binding protein, Teleost fish, Genome duplication, Physiology, Comparative biology, Gene family evolution",

author = "\{Garcia de la Serrana\}, Daniel and Macqueen, \{Daniel J.\}",

note = "DGS would like to thank the Marine Alliance Science Technology Scotland (MASTS) for their support. MASTS is funded by the Scottish Funding Council (grant reference HR09011) and contributing institutions.",

year = "2018",

month = mar,

day = "12",

doi = "10.3389/fendo.2018.00080",

language = "English",

volume = "9",

journal = "Frontiers in Endocrinology",

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TY - JOUR

T1 - Insulin-like growth factor binding proteins of teleost fishes

AU - Garcia de la Serrana, Daniel

AU - Macqueen, Daniel J.

N1 - DGS would like to thank the Marine Alliance Science Technology Scotland (MASTS) for their support. MASTS is funded by the Scottish Funding Council (grant reference HR09011) and contributing institutions.

PY - 2018/3/12

Y1 - 2018/3/12

N2 - The insulin-like growth factor (IGF) binding protein (IGFBP) family has a broad range of physiological functions and a fascinating evolutionary history. This review focuses on the IGFBPs of teleost fishes, where genome duplication events have diversified gene repertoire, function and physiological regulation - with six core IGFBPs expanded into a family of over twenty genes in some lineages. In addition to briefly summarizing the current state of knowledge on teleost IGFBP evolution, function and expression-level regulation, we highlight gaps in our understanding, and promising areas for future work.

AB - The insulin-like growth factor (IGF) binding protein (IGFBP) family has a broad range of physiological functions and a fascinating evolutionary history. This review focuses on the IGFBPs of teleost fishes, where genome duplication events have diversified gene repertoire, function and physiological regulation - with six core IGFBPs expanded into a family of over twenty genes in some lineages. In addition to briefly summarizing the current state of knowledge on teleost IGFBP evolution, function and expression-level regulation, we highlight gaps in our understanding, and promising areas for future work.

KW - Insulin-like growth factor binding protein

KW - Teleost fish

KW - Genome duplication

KW - Physiology

KW - Comparative biology

KW - Gene family evolution

UR - https://www.scopus.com/pages/publications/85043485336

U2 - 10.3389/fendo.2018.00080

DO - 10.3389/fendo.2018.00080

M3 - Review article

SN - 1664-2392

VL - 9

JO - Frontiers in Endocrinology

JF - Frontiers in Endocrinology

M1 - 80

ER -

Insulin-like growth factor binding proteins of teleost fishes

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