Projects per year
Abstract
There are many new advances in neuroscience and mental health which should lead to a greater understanding of the neurobiological dysfunction in neuropsychiatric disorders and new developments for early, effective treatments. To do this, a biomarker approach combining genetic, neuroimaging, cognitive and other biological measures is needed. The aim of this article is to highlight novel approaches for pharmacological and non-pharmacological treatment development. This article suggests approaches that can be taken in the future including novel mechanisms with preliminary clinical validation to provide a toolbox for mechanistic studies and also examples of translation and back-translation. The review also emphasizes the need for clinician-scientists to be trained in a novel way in order to equip them with the conceptual and experimental techniques required, and emphasizes the need for private-public partnership and pre-competitive knowledge exchange. This should lead the way for important new holistic treatment developments to improve cognition, functional outcome and well-being of people with neuropsychiatric disorders.
Original language | English |
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Pages (from-to) | 2438-2444 |
Number of pages | 7 |
Journal | Neuroscience and Biobehavioral Reviews |
Volume | 37 |
Issue number | 10 Part 1 |
DOIs | |
Publication status | Published - Dec 2013 |
Keywords
- Translation
- Back-translation
- Pharmacological tool box
- Cognitive and psychosocial treatments
- Novel drug development
- Biomarkers
- Neurobiological mechanisms
- Neuropsychiatric disorders
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Dive into the research topics of 'Innovative solutions to novel drug development in mental health'. Together they form a unique fingerprint.Projects
- 1 Finished
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Royal Society - Industry Fellowship: Royal Society Industry Fellowship
Brown, V. J. (PI)
1/02/07 → 31/01/12
Project: Fellowship