Abstract
Objectives The aim of this paper is to study the influence of albumin content, from 5 to 45 g/L, on copper dissolution and compounds composition in a simulated uterine solution.
Methods Experiments were performed in atmospheric pressure conditions and with an additional oxygen pressure of 0.2 atmospheres, at 6.3 and 8.0 pH values, and at a temperature of 37 +/- 0.1 degrees C for 1, 3, 7, and 30 days experimentation time.
Results The copper dissolution rate has been determined using absorbance measurements, finding the highest value for pH 8.0, 35 g/L albumin, and with an additional oxygen pressure of 0.2 atmospheres: 674 mu g/day for 1 day, and 301 mu g/day for 30 days. X-ray photoelectron spectroscopy (XPS) results show copper(II) as the main copper oxidation state at pH 8.0; and copper(l) and metallic copper at pH 6.3.
Conclusions The presence of albumin up to 35 g/L, accelerates copper dissolution. For high albumin content a stabilisation on the copper dissolution takes place. Corrosion product layer morphology is poorly protective, showing paths through which copper ions can release.
| Original language | English |
|---|---|
| Pages (from-to) | 123-130 |
| Number of pages | 8 |
| Journal | European Journal of Contraception and Reproductive Health Care |
| Volume | 10 |
| DOIs | |
| Publication status | Published - Jun 2005 |
Keywords
- copper
- simulated uterine fluid
- albunuin
- oxygen pressure
- pH
- XPS and SEM
- INTRAUTERINE CONTRACEPTIVE DEVICES
- CORROSION PRODUCTS
- HUMAN-SPERMATOZOA
- IONS