In vitro photo-release of a TRPV1 agonist

J. L. Carr, K. N. Wease, M. P. Van Ryssen, S. Paterson, B. Agate, K. A. Gallagher, Christian Thomas Alcuin Brown, R. H. Scott, Stuart John Conway

Research output: Contribution to journalArticlepeer-review

Abstract

Intracellular photolysis of a novel 'caged' capsaicin analogue results in in vitro activation of the capsaicin receptor TRPV1. (c) 2005 Elsevier Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)208-212
Number of pages5
JournalBioorganic and Medicinal Chemistry Letters
Volume16
Issue number1
DOIs
Publication statusPublished - 1 Jan 2006

Keywords

  • ANALGESIC AGENTS
  • CAPSAICIN RECEPTOR
  • PROTECTING GROUPS
  • ANALOGS
  • PAIN
  • ANTAGONISTS
  • REGION
  • MECHANISMS
  • DISCOVERY
  • CHANNELS

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