Abstract
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) of proteins was performed on a range of polytetrafluoroethylene (PTFE) surfaces. Sinapinic acid and alpha-cyano-4-hydroxycinnamic acid matrices were compared and the order of application varied to identify the best combination for each surface. It is demonstrated that the use of a PTFE surface improves the intensity of signals obtained for higher molecular weight proteins. Copyright (C) 2003 John Wiley Sons, Ltd.
Original language | English |
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Pages (from-to) | 598-602 |
Number of pages | 5 |
Journal | Rapid Communications in Mass Spectrometry |
Volume | 17 |
Issue number | 6 |
DOIs | |
Publication status | Published - Mar 2003 |
Keywords
- SAMPLE SUPPORT
- GEL-ELECTROPHORESIS
- MEMBRANE
- PEPTIDES